Chronic pain is a leading cause of disability globally and associated with enormous health-
care costs. The discrepancy between the extent of tissue damage and the magnitude of …

Studies have suggested that quantitative sensory testing (QST) might hold a predictive value
for the development of chronic postoperative pain and the response to pharmacological …

Central sensitisation is assumed to be one of the underlying mechanisms for chronic low
back pain. Because central sensitisation is not directly assessable in humans, the term …

Altered pronociceptive and antinociceptive mechanisms are often implicated in painful
conditions and have been increasingly studied over the past decade. For some painful …

Introduction Treating chronic low back pain (LBP) can be challenging, and the most effective
pharmacological therapy is controversial. The present systematic review investigated the …

Objective Recent studies suggest that sensory phenotyping may provide critical information
for the diagnosis and management of patients with chronic neuropathic pain (NP). However …

Abstract Background and Objective Metabolomics deals with the identification and
quantification of small molecules (metabolites) in biological samples. As metabolite levels …

Objective: Finding an effective preventive agent for the individual migraineur is often long
and frustrating. An individual-specific, efficacy-predicting tool would be invaluable in …

Background Current clinical phenotyping of musculoskeletal pain provides very limited
evidence‐based support to personalized medicine. This paper discusses the potential of …

Objectives: Patients with low back pain (LBP) often demonstrate pain sensitization, high
degree of pain catastrophizing, and psychological distress. This study investigated whether …