Abstract Background The International Society on Thrombosis and Haemostasis (ISTH)
released overt disseminated intravascular coagulation (DIC) diagnostic criteria in 2001 …

Sepsis is a major global health problem that results from a dysregulated and uncontrolled
host response to infection, causing organ failure. Despite effective anti-infective therapy and …

The vascular endothelium is crucial for the maintenance of vascular homeostasis. Moreover,
in sepsis, endothelial cells can acquire new properties and actively participate in the host's …

Disseminated intravascular coagulation (DIC) has been understood as a consumptive
coagulopathy. However, impaired hemostasis is a component of DIC that occurs in a …

OBJECTIVE: Vaccine-induced immune thrombocytopenia (VITT) is a new syndrome
occurring primarily in healthy young adults, with a female predominance, after receiving the …

Disseminated intravascular coagulation (DIC) is not a disease criterion but a
pathomechanistic process that accompanies various underlying diseases. According to the …

COVID-19 sepsis is characterized by acute respiratory distress syndrome (ARDS) as a
consequence of pulmonary tropism of the virus and endothelial heterogeneity of the host …

The role of the vascular microenvironment is increasingly studied in acute myeloid
leukaemia (AML). Complex interactions between endothelial cells (ECs) and pre-leukaemic …

Complementopathy, endotheliopathy, and coagulopathy following a traumatic injury are key
pathophysiological mechanisms potentially associated with multiple-organ failure (MOF) …

Endotheliopathy, according to the “two-activation theory of the endothelium”, can be
triggered by the activated complement system in critical illnesses, such as sepsis and …