Glucocorticoids have pleiotropic effects that are used to treat diverse diseases such as
asthma, rheumatoid arthritis, systemic lupus erythematosus and acute kidney transplant …

The antituberculosis drug rifampicin (rifampin) induces a number of drug-metabolising
enzymes, having the greatest effects on the expression of cytochrome P450 (CYP) 3A4 in …

Tuberculosis is a serious opportunistic infection in transplant recipients. On the basis of the
compilation of published reports in the literature, the incidence of Mycobacterium …

Solid-organ transplantation is a therapeutic option for many human diseases. Infections are
a major complication of solid-organ transplantation. All candidates should undergo a …

Up to 10% of patients with renal disease receiving recombinant human erythropoietin
(rHuEPO) therapy show poor responsiveness to the drug. Even in patients who do respond …

Background. Tuberculosis is unusual in transplant recipients. The incidence, clinical
manifestations, and optimal treatment of this disease in this population has not been …

Rifampicin is an inducer of hepatic drug metabolising enzymes. This results in interactions
with several drugs including oral anticoagulants, hypoglycaemics, and contraceptives …

The growth of knowledge in the field of the pharmacokinetics of prednisolone/prednisone
has been slow for several reasons. First, convenient and specific methods for measuring …

Mycobacterial infections represent a growing challenge for solid organ transplant recipients
(SOT). The adverse effects of tuberculosis (TB) therapy present a major difficulty, due to the …

Despite the success of lung transplantation, infection is one of the leading causes of
morbidity and mortality. Mycobacterial infections have been reported rarely, with the majority …