Reduced health-related quality of life, fatigue, anxiety and depression affect COVID-19 patients in the long-term after chronic critical illness

M Egger, C Wimmer, S Stummer, J Reitelbach… - Scientific reports, 2024 - nature.com
The term chronic critical illness describes patients suffering from persistent organ
dysfunction and prolonged mechanical ventilation. In severe cases, COVID-19 led to chronic …

The impact of frailty on the outcomes of COVID-19 patients with persistent critical illness: A population-based cohort study

W Bonavia, R Tiruvoipati, MP Reddy, D Pilcher… - medRxiv, 2023 - medrxiv.org
Abstract Objectives Persistent critical illness (PerCI,≥ 10 days in Intensive Care Unit [ICU])
is defined as the time from ICU admission when patients' antecedent characteristics define …

Prior physical illness predicts death better than acute physiological derangement on intensive care unit admission in COVID-19: A Swedish registry study

K Stattin, M Hultström, R Frithiof, M Lipcsey, R Kawati - Plos one, 2023 - journals.plos.org
COVID-19 is associated with prolonged intensive care unit (ICU) stay and considerable
mortality. The onset of persistent critical illness, defined as when prior illness predicts death …

[HTML][HTML] Characterising biological mechanisms underlying ethnicity-associated outcomes in COVID-19 through biomarker trajectories: a multicentre registry analysis

YI Wan, ZA Puthucheary, RM Pearse… - British Journal of …, 2023 - Elsevier
Background Differences in routinely collected biomarkers between ethnic groups could
reflect dysregulated host responses to disease and to treatments, and be associated with …

CCL2 Promotes Novel Coronavirus-Mediated Inflammatory Responses on Macrophages

F Ding, M Dai, X Kang, X Zhang, L Li… - Clinical and …, 2023 - utpjournals.press
Purpose The hyperinflammatory response is one of the main complications associated with
novel coronavirus disease 2019 (COVID-19), and there is no effective treatment for cytokine …

[HTML][HTML] Persistent Critical Illness and Long-Term Outcomes in Patients With COVID-19: A Multicenter Retrospective Cohort Study

RR Ling, W Bonavia, MP Reddy, D Pilcher… - Critical Care …, 2024 - journals.lww.com
OBJECTIVES: A nontrivial number of patients in ICUs experience persistent critical illness
(PerCI), a phenomenon in which features of the ICU course more consistently predict …

The interplay between frailty status and persistent critical illness on the outcomes of patients with critical COVID-19: A population-based retrospective cohort study

W Bonavia, RR Ling, R Tiruvoipati, MP Reddy… - Australian Critical …, 2024 - Elsevier
Abstract Objectives Persistent critical illness (PerCI) occurs when the patient's prolonged
intensive care unit (ICU) stay results in complications that become the primary drivers of their …

Deep Learning and Graph Analytics for Explainable Modeling of Clinical Time-Varying Data Associated with Infectious Diseases

S Martínez Agüero - 2024 - burjcdigital.urjc.es
Esta tesis doctoral realiza una investigación de las herramientas de ciencia de datos para
abordar dos problemas incipientes en entornos clínicos modernos: la Multiresistencia …