The hexokinase-catalysed phosphorylation of glucose by ATP occurs in all eukaryotic cells
as the first step in the utilization of glucose, and the reaction is also widespread in …

The transfer of a phosphoryl moiety from ATP to an acceptor group is an essential step,
frequently the initial step, in the metabolism of many molecules. Hence, kinases represent a …

Warburg effect is a dominant phenotype of most cancer cells. Here we show that this
phenotype depends on its environment. When cancer cells are under regular culture …

A tumorigenic anchorage-dependent cell line (H-91) was established in culture from an azo-
dye-induced rat ascites hepatoma. When grown in a glucose-containing medium the cells …

Cellular bio-energetic metabolism and mitochondria are recognized as potential targets for
anticancer agents, due to the numerous relevant peculiarities cancer cells exhibit …

Publisher Summary There has been the identification of two native hexokinases in baker's
yeast, the resolution of the question of the molecular weight and subunit structure of each …

1. The effects of protein concentration and ionic strength on the adsorption of the individual
glycolytic enzymes to F-actin and F-actin--trypomyosin--troponin have been studied. 2 …

In rapidly growing, highly glycolytic hepatoma cells as much as 65% of the total cell
hexokinase is bound to the outer mitochondrial membrane [Parry, DM, & Pedersen …

Hexokinase (ATP: d-hexose 6-phosphotransferase, EC 2.7. 1.1) ushers glucose into the
theater of cellular metabolism: Glucose+ ATP⋅ Mg++⇌ Glucose-6-P+ ADP⋅ Mg++ https://s3 …

Although much is known about the biochemical regulation of glycolytic enzymes, less is
understood about how they are organized inside cells. We systematically examine the …