Rapid purification of mitochondrial hexokinase from rat brain by a single affinity chromatography step on Affi-Gel blue

JE Wilson - 1989 - Taylor & Francis
The mitochondrial hexokinase from rat brain, selectively released from mitochondria by the
action of glucose 6-phosphate, can be purified to greater than 90% homogeneity by a single …

Kinetic models of metabolism in intact cells, tissues, and organisms

BE WRIGHT, PJ KELLY - Current topics in cellular regulation, 1981 - Elsevier
Publisher Summary This chapter discusses the kinetic models of metabolism in intact cells,
tissues, and organisms. Models can provide conceptual insights and help one think and ask …

Mitochondrial, plastid and cytosolic isozymes of hexokinase from developing endosperm of Ricinus communis

JA Miernyk, DT Dennis - Archives of Biochemistry and Biophysics, 1983 - Elsevier
Ion-filtration chromatography on DEAE-Sephadex A-25 at pH 5.5 resolved the total
hexokinase activity in a 27,000 g supernatant prepared from developing castor oil (Ricinus …

Alterations in glucose metabolism in chick embryo cells transformed by Rous sarcoma virus: Transformation-specific changes in the activities of key enzymes of the …

M Singh, VN Singh, JT August, BL Horecker - Archives of biochemistry and …, 1974 - Elsevier
Abstract Effects of transformation by Rous sarcoma virus of Schmidt-Ruppin strain on the
activities of key enzymes of the glycolytic and the hexose monophosphate shunt pathways in …

The localization of latent brain hexokinase on synaptosomal mitochondria

JE Wilson - Archives of biochemistry and biophysics, 1972 - Elsevier
Fractionation of rat brain homogenates on linear 0.8–1.6-m sucrose gradients results in
partial resolution of the overt and latent forms of hexokinase. The overt activity sediments …

Effect of neutral salts on the interaction of rat brain hexokinase with the outer mitochondrial membrane

PL Felgner, JE Wilson - Archives of biochemistry and biophysics, 1977 - Elsevier
Abstract The glucose 6-phosphate (Glc-6-P)-induced solubilization of mitochondrial
hexokinase (ATP: d-hexose 6-phosphotransferase, EC 2.7. 1.1) from rat brain can be …

Mg++ requirement for MtHK binding, and Mg++ stabilization of mitochondrial membranes via activation of MtHK & MtCK and promotion of mitochondrial permeability …

S Golshani-Hebroni - Gene, 2016 - Elsevier
Evidence points to magnesium's antioxidant, anti-necrotic, and anti-apoptotic effects in
cardio-and neuroprotection. With magnesium being involved in over 300 biochemical …

Rat brain hexokinase: further studies on the specificity of the hexose and hexose 6-phosphate binding sites

JE Wilson, V Chung - Archives of biochemistry and biophysics, 1989 - Elsevier
Based on the lack of correlation between the ability of various hexoses to serve as substrate
and the ability of the corresponding hexose 6-phosphates to inhibit brain hexokinase (ATP …

Protein kinase activity of rat brain hexokinase

V Adams, LD Griffin, BD Gelb, ERB McCabe - Biochemical and biophysical …, 1991 - Elsevier
Abstract Hexokinase 1 (HK1) purified from rat brain exhibits protein kinase activity, including
autophosphorylation and phosphorylation of histone H2A. This protein kinase activity is …

Brain hexokinase: the preparation of inner and outer mitochondrial membranes

PA Craven, PJ Goldblatt, RE Basford - Biochemistry, 1969 - ACS Publications
Patricia A. Craven,! Peter J. Goldblatt,! and RE Basford abstract: Three different methods
were used to prepare inner and outer membranes of brain mitochondria. The digitonin and …