The application of polygenic scores has transformed our ability to investigate whether and
how genetic and environmental factors jointly contribute to the variation of complex traits …

While genome-wide association studies have identified susceptibility variants for numerous
traits, their combined utility for predicting broad measures of health, such as mortality …

The aim of this review is to explore the relationship between melatonin, free radicals, and
non-excitatory amino acids, and their role in stroke and aging. Melatonin has garnered …

Background: Atrial fibrillation (AF) is associated with a five-fold increased risk of ischemic
stroke. A portion of this risk is heritable; however, current risk stratification tools (CHA2DS2 …

Background: Genome-wide association studies have identified single-nucleotide
polymorphisms that are associated with an increased risk of stroke. We sought to determine …

Background Despite the well‐established capacity of physical activity to reduce blood
pressure, the associations between physical activity with cardiovascular disease (CVD) …

Background Factors of lifestyle may have a major impact on liver-related morbidity and
mortality. We examined independent and joint effects of lifestyle risk factors on fatty liver …

In arguably the most influential public health article ever written,“Sick Individuals and Sick
Populations,” Geoffrey Rose1 described and appraised 2 mainstream strategies for primary …

Background The presence of a threshold effect has been proposed, suggesting that
beneficial effects from vitamin D supplementation may only be present when the vitamin D …

Background The impact of integrated lifestyles on health has attracted a lot of attention. It
remains unclear whether adherence to low-risk healthy lifestyle factors is protective in …