Early prediction of risk of cardiovascular disease (CVD), including stroke, is a cornerstone of
disease prevention. Clinical risk scores have been widely used for predicting CVD risk from …

Objective To construct a polygenic risk score (PRS) for stroke and evaluate its utility in risk
stratification and primary prevention for stroke. Methods Using a meta-analytic approach and …

Background The prospective association of depression with incident sarcopenia remains
unknown, as does whether such an association is modified by a healthy lifestyle. Thus, the …

Background and Purpose: Assessing whether modifiable risk factors are causally associated
with stroke risk is important in planning public health measures, but determining causality …

Background Whether the lifestyle is associated with the risk of psoriasis in the presence of
different genetic risk levels remains unknown. Objective To examine the gene-behavior …

OBJECTIVE Evidence is limited regarding the associations between vitamin D status and
microvascular complications in individuals with type 2 diabetes (T2D), among whom vitamin …

Abstract Background and Aims Air pollutants are important contributors to cardiovascular
diseases, but associations between long-term exposure to air pollutants and the risk of …

Cardiovascular disease (CVD) is a leading cause of morbidity and mortality globally.
Although CVD events do not typically manifest until older adulthood, CVD develops …

The purpose of this paper is to help readers choose an appropriate observational study
design for measuring an association between an exposure and disease incidence. We …

Background Cardiometabolic disease (CMD) increases the risk of mortality, but the extent to
which this can be offset by adherence to a healthy lifestyle is unknown. We aimed to …