Three different spermatogenesis loci have been mapped on the Y chromosome and named
“azoospermia factors”(AZFa, b, and c). Deletions in these regions remove one or more of the …

Human chromosome deletions in Yq11 seem to occur frequently as de novo mutation events
in men with idiopathic azoospermia or severe oligozoospermia. However, the molecular …

Cytogenetic and molecular deletion analyses of azoospermic and oligozoospermic males
have suggested the existence of AZoospermia Factor (s)(AZF) residing in deletion intervals …

BACKGROUND: Severe spermatogenic compromise may be the result of a Y-chromosomal
deletion of the AZFc region. Prior studies are limited to relatively small numbers of AZFc …

The heterogeneity of the protocols employed and of the results published, together with the
increasing diffusion of this diagnostic procedure, suggested the necessity of a quality control …

Idiopathic Sertoli cell-only syndrome (SCOS) Is characterized by azoospermia, small testes,
absence of germ cells In the testes, elevated Mick stimulating hormone and normal …

A total of 3179 patients were screened for Y-chromosome microdeletions and 821 patients
for partial AZFc deletions. Thirty-nine Y-chromosomal microdeletions were found (2.4% of …

Deletion of the AZFc region of the Y chromosome is the most frequent molecularly defined
cause of spermatogenic failure. We report three unrelated men in whom azoospermia or …

Chromosomal abnormalities are thought to be a major contributor to the genetic risks of
infertility treatment by intracytoplasmic sperm injection (ICSI). Apart from abnormalities …

The human DAZ gene family is expressed in germ cells and consists of a cluster of nearly
identical DAZ (deleted in azoospermia) genes on the Y chromosome and an autosomal …