The acquired immunodeficiency syndrome is a new disease whose cause is unknown but is
almost surely due to a transmissible agent, most likely a virus. The disease is clearly spread …

Eighty-eight bone marrow transplant recipients were studied for development of
cytomegalovirus (CMV) infections and associated cytotoxic lymphocyte responses. Sixty-one …

Although there are a number of excellent current reviews on one or another aspect of
cytomegalovirus, the last comprehensive treatment of this subject was that of Krech et …

The recently described acquired immune deficiency syndrome (AIDS) is characterized by
the occurrence of severe opportunistic infections and an aggressive form of Kaposi's …

The role of HLA-DR+ cells in NK activity against CMV-infected FS4 foreskin fibroblasts and
K562 erythroleukemia cells was examined. When nonadherent PBMC were depleted of …

Thirty renal transplant recipients were studied prospectively to evaluate the relationship of
cytomegalovirus-specific cytotoxic lymphocyte responses to clinical outcome during …

Cells normally insensitive to human natural killer (NK) activity were rendered susceptible by
infection with HSV-1. The cytotoxic effector cell was a nonadherent, non-T, non-B …

NK cells are critical effector cells of the innate immune response to malignancy and
infection. These cells have a wide array of direct antiviral activities and have been critically …

Materials and Methods Study subjects. The subjects in our study included 36 patients with
AIDS who had opportunistic infections (AIDS-OI); 20 patients with AIDS who had Kaposi's …

Defining causality between an agent-be it a virus, bacteria, or chemical—and a disease is
the principal aim of biomedical research. Achievement of this lofty goal is hampered when …