Pyridoxine dependency was one of the first genetically mediated seizure disorders to be
recognized. However, the biochemical abnormality and gene locus are still unknown …

Infantile spasms is one of the “catastrophic childhood epilepsies” because of the difficulty in
controlling seizures and the association with mental retardation. However, early recognition …

Objective To determine the underlying etiologies in a contemporary cohort of infants with
infantile spasms and to examine response to treatment. Methods Identification of the …

OBJECTIVE To study the epidemiology of pyridoxine dependent seizures and other forms of
pyridoxine responsive seizures. DESIGN Monthly notifications to the British Paediatric …

To facilitate clinical research on pyridoxine-dependent seizures (PDS), a rare disease
registry was established for affected patients in the United States and Canada. From 1999 to …

West syndrome is a multi-etiological condition. Recent progress in perinatal medicine and
the recent development of new neuroimaging techniques may have changed the etiological …

Purpose: Before 1986, the spectrum of childhood epilepsies, including Lennox‐Gastaut
syndrome (LGS) and Doose syndrome (DS), known collectively as “epilepsia myoclonica …

No other epilepsy more substantially combines cryptogenicity and intractability than does
Lennox‐Gastaut Syndrome. Although antecedent neurological conditions have preceeded …

Purpose: The efficacy of a protocol consisting of vigabatrin (VGB) as the first and
adrenocorticotropic hormone (ACTH) or valproate (VPA) as the second drug was studied in …

To describe the poorly known characteristics of epilepsy during infancy in focal cortical
dysplasia (FCD), one of the most frequent cause of infantile epilepsy. All 28 patients with …