Rab proteins form the largest branch of the Ras superfamily of GTPases. They are localized
to the cytoplasmic face of organelles and vesicles involved in the biosynthetic/secretory and …

Proper vesicle tethering and membrane fusion at the cell plate are essential for cytokinesis.
Both the vesicle tethering complex exocyst and membrane fusion regulator KEULE were …

Several recent studies have revealed the existence of a conserved oligomeric Golgi (COG)
complex consisting of several novel proteins as well as known Golgi proteins that were …

In Saccharomyces cerevisiae, clathrin is necessary for localization of trans-Golgi network
(TGN) membrane proteins, a process that involves cycling of TGN proteins between the TGN …

The molecular basis of the selectivity and the details of the vesicle formation in endocytic
and secretory pathways are still poorly known and most probably involve as yet unidentified …

The Hermansky–Pudlak syndrome defines a group of genetic disorders characterized by
defective lysosome‐related organelles such as melanosomes and platelet dense bodies …

Next to the protein-based machineries composed of small G-proteins, coat complexes,
SNAREs and tethering factors, the lipid-based machineries are emerging as important …

Rab7 has been shown to regulate the late steps of the endocytic pathway. In bone-resorbing
osteoclasts, it is involved in formation of the ruffled border, which is a late endosomal-like …

Hyphal tip growth, the hallmark of the fungi, requires highly polarized and localized
exocytosis, but how this requirement is met is unknown. Members of conserved protein …

The eukaryotic Golgi apparatus is characterized by a stack of flattened cisternae that are
surrounded by transport vesicles. The organization and function of the Golgi require Golgi …