Environmental exposure plays a major role in the development of allergic diseases. The
exposome can be classified into internal (eg, aging, hormones, and metabolic processes) …

Vernal keratoconjunctivitis (VKC) is a chronic, bilateral corneal and conjunctival problem
which typically presents in young individuals. VKC is characterized by itching, photophobia …

MicroRNAs are non-coding RNAs that serve as regulatory molecules in a variety of
pathways such as inflammation, metabolism, homeostasis, cell machinery, and …

Since the 1960 s, our health has been compromised by exposure to over 350,000 newly
introduced toxic substances, contributing to the current pandemic in allergic, autoimmune …

The structural and functional integrity of the ocular surface, a continuous epithelial structure
comprised of the cornea, the conjunctiva, and the ductal surface of the lacrimal as well as …

Allergic rhinitis is a highly prevalent chronic inflammatory disorder of the nasal mucosa that
poses a significant burden on patients' health and quality of life. Current therapies for …

It is now longer than half a century, humans, animals, and nature of the world are under the
influence of exposure to many newly introduced noxious substances. These exposures are …

The epithelial barrier theory links the recent rise in chronic non-communicable diseases,
notably autoimmune and allergic disorders, to environmental agents disrupting the epithelial …

The “epithelial barrier hypothesis” proposes that genetic predisposition to epithelial barrier
damage, exposure to various epithelial barrier–damaging agents and chronic periepithelial …

Vernal keratoconjunctivitis (VKC) is a complex and multifactorial disease process that
employs Th2 cell-mediated immunologic processes, which involves the overexpression of …