[HTML][HTML] Allergic Conjunctivitis Management: Update on Ophthalmic Solutions

A Leonardi, L Quintieri, IJ Presa, JM LLoves… - Current Allergy and …, 2024 - Springer
Abstract Purpose of Review The aim of this review, is to present an updated revision of
topical management of SAC and PAC, based on the available scientific evidence and …

[HTML][HTML] Characterization and functional performance of a commercial human conjunctival epithelial cell line

L García-Posadas, I Romero-Castillo, N Katsinas… - Experimental Eye …, 2022 - Elsevier
The conjunctiva is a complex tissue that covers the eye beginning at the corneal limbus and
extending over the inner surfaces of the eyelids. Due to its important functions in maintaining …

[HTML][HTML] Stachyose ameliorates obesity-related metabolic syndrome via improving intestinal barrier function and remodeling gut microbiota

N He, H Wang, S Yu, K Chen, Z Wu, X Lin… - Journal of Functional …, 2024 - Elsevier
In this study, oral supplementation of stachyose significantly improved HFD-induced MetS
symptom, including overweight, hyperlipidemia, hepatic steatosis and system-wide …

Evidence of epithelial remodelling but not epithelial–mesenchymal transition by transcriptome profiling in vernal keratoconjunctivitis.

A Leonardi, P Daull, U Rosani, F Cavarzeran… - Allergy, 2022 - search.ebscohost.com
Vernal keratoconjunctivitis (VKC) is a severe type 2 ocular disease associated with corneal
involvement, tissue remodelling, potential complications and visual impairment. 1 The tarsal …

[HTML][HTML] Endoplasmic reticulum stress and unfolded protein response in vernal keratoconjunctivitis

A Leonardi, A Donato, U Rosani… - … & Visual Science, 2024 - iovs.arvojournals.org
Purpose: Vernal keratoconjunctivitis (VKC) is an ocular allergic disease characterized by a
type 2 inflammation, tissue remodeling, and low quality of life for the affected patients. We …

TLR7 Agonists Modulate the Activation of Human Conjunctival Epithelial Cells Induced by IL-1β via the ERK1/2 Signaling Pathway

L Wang, S Li, K Cai, Y Xiao, L Ye - Inflammation, 2023 - Springer
Conjunctival epithelia cells play an important role in the development of allergic reactions.
TLR7 agonists have been shown in studies to increase the body's immunological tolerance …

Atopic dermatitis and ocular allergy: common mechanisms and uncommon questions

D Ghosh, TB Mersha - Current Opinion in Allergy and Clinical …, 2023 - journals.lww.com
Modern cytokine-targeted therapies for AD showed elevated risk for developing
conjunctivitis. Recently developed noninvasive sampling techniques should be leveraged to …

[HTML][HTML] Impact of inflammasomes on the ocular surface

GS Stinnett, CH Kuo, SJ Ono - Current Opinion in Allergy and …, 2024 - journals.lww.com
Research efforts continue to characterize the types of inflammasomes and activators of
these in inflammatory ocular surface conditions. Various therapies targeting specific …

Atopische Keratokonjunktivitis: Pathophysiologie, Klinik und potenzielle neue Therapiekonzepte

T Lapp, C Mann, T Jakob, T Reinhard… - Klinische …, 2024 - thieme-connect.com
Atopic dermatitis (AD) is a chronic recurrent inflammatory skin disease with a bipolar age
distribution in childhood, adolescence and middle adulthood. Up to 50% of AD patients …

[HTML][HTML] Aqueous-deficient dry eye exacerbates signs and symptoms of allergic conjunctivitis in mice

T Kishimoto, W Ishida, I Nakajima, K Fukuda… - International Journal of …, 2022 - mdpi.com
Dry eye disease (DED) and allergic conjunctivitis affect a large number of patients, and
many patients usually have both symptoms. We investigated the interactions between DED …