Molecular Landscape of LncRNAs in Prostate Cancer: A focus on pathways and therapeutic targets for intervention

S Mirzaei, MDA Paskeh, E Okina, MH Gholami… - Journal of Experimental …, 2022 - Springer
Background One of the most malignant tumors in men is prostate cancer that is still incurable
due to its heterogenous and progressive natures. Genetic and epigenetic changes play …

(Nano) platforms in bladder cancer therapy: Challenges and opportunities

M Ashrafizadeh, A Zarrabi… - Bioengineering & …, 2023 - Wiley Online Library
Urological cancers are among the most common malignancies around the world. In
particular, bladder cancer severely threatens human health due to its aggressive and …

[HTML][HTML] A bioinformatics analysis, pre-clinical and clinical conception of autophagy in pancreatic cancer: complexity and simplicity in crosstalk

M Ashrafizadeh, W Zhang, R Zou, G Sethi… - Pharmacological …, 2023 - Elsevier
Pancreatic cancer (PC) is a serious gastrointestinal tract disease for which the 5-year
survival rate is less than 10%, even in developed countries such as the USA. The genomic …

Chitosan‐based nanoscale systems for doxorubicin delivery: Exploring biomedical application in cancer therapy

M Ashrafizadeh, K Hushmandi… - Bioengineering & …, 2023 - Wiley Online Library
Green chemistry has been a growing multidisciplinary field in recent years showing great
promise in biomedical applications, especially for cancer therapy. Chitosan (CS) is an …

[HTML][HTML] Progress in targeting PTEN/PI3K/Akt axis in glioblastoma therapy: Revisiting molecular interactions

M Hashemi, S Etemad, S Rezaei, S Ziaolhagh… - Biomedicine & …, 2023 - Elsevier
Glioblastoma (GBM) is one of the most malignant cancers of central nervous system and due
to its sensitive location, surgical resection has high risk and therefore, chemotherapy and …

[HTML][HTML] LncRNA-miRNA axis in tumor progression and therapy response: An emphasis on molecular interactions and therapeutic interventions

M Entezari, A Taheriazam, S Orouei, S Fallah… - Biomedicine & …, 2022 - Elsevier
Epigenetic factors are critical regulators of biological and pathological mechanisms and they
could interact with different molecular pathways. Targeting epigenetic factors has been an …

[HTML][HTML] Paclitaxel and docetaxel resistance in prostate cancer: Molecular mechanisms and possible therapeutic strategies

M Hashemi, MA Zandieh, Y Talebi… - Biomedicine & …, 2023 - Elsevier
Prostate cancer is among most malignant tumors around the world and this urological tumor
can be developed as result of genomic mutations and their accumulation during progression …

microRNAs (miRNAs) in glioblastoma multiforme (GBM)—recent literature review

M Makowska, B Smolarz, H Romanowicz - International Journal of …, 2023 - mdpi.com
Glioblastoma multiforme (GBM) is the most common, malignant, poorly promising primary
brain tumor. GBM is characterized by an infiltrating growth nature, abundant vascularization …

Targeting Nrf2 in ischemia-reperfusion alleviation: From signaling networks to therapeutic targeting

M Sadrkhanloo, M Entezari, S Orouei, A Zabolian… - Life Sciences, 2022 - Elsevier
The nuclear factor erythroid 2-related factor 2 (Nrf2) is a master regulator of redox balance
and it responds to various cell stresses that oxidative stress is the most well-known one. The …

Noncoding RNA as an influential epigenetic modulator with promising roles in cancer therapeutics

L Roy, O Chatterjee, D Bose, A Roy, S Chatterjee - Drug Discovery Today, 2023 - Elsevier
The epigenetic landscape has an important role in cellular homeostasis and its deregulation
leads to cancer. Noncoding (nc) RNA networks function as major regulators of cellular …