BACKGROUND:: Systemic corticosteroids are known to increase diabetes risk, but the
effects of high-dose inhaled corticosteroids are unknown. We assessed whether the use and …

Background: A clinical model is needed to compare inhaled corticosteroids (ICSs) with
respect to efficacy. Objective: The purpose of this investigation was to compare the relative …

Background: Morbidity associated with cardiovascular disease is increasing in the HIV-
infected population. We aimed to study the impact of HIV and of antiretrovirals on acute …

Chronic obstructive pulmonary disease (COPD) is a major respiratory illness in Canada that
is both preventable and treatable. Our understanding of the pathophysiology of this complex …

Topical ophthalmic, oral, and intravenous corticosteroids have long been associated with
ocular side effects. Recent data suggest that inhaled corticosteroids are also associated with …

Corticosteroids, used prudently, are one of the most potent and effective modalities available
in the treatment of ocular inflammation. However, they can produce a plethora of adverse …

While the pharmacological management of chronic obstructive pulmonary disease (COPD)
has evolved from the drugs used to treat asthma, the treatment models are different and the …

In this article, we focus on the scientific evidence from randomised trials supporting
treatment with inhaled corticosteroids (ICS) in chronic obstructive pulmonary disease …

Conventional nonsteroidal antiinflammatory drugs (NSAIDs) are associated with acute renal
failure, but cyclooxygenase-2 inhibitors have not been comparatively evaluated. The authors …

COPD is prevalent in Western society and its incidence is rising in the developing world.
Acute exacerbations of COPD, about 50% of which are unreported, lead to deterioration in …