Uric acid (UA) is an end product of purine metabolism in humans and great apes. UA acts as
an antioxidant and it accounts for 50% of the total antioxidant capacity of biological fluids in …

Uric acid is synthesized mainly in the liver, intestines and the vascular endothelium as the
end product of an exogenous pool of purines, and endogenously from damaged, dying and …

Serum uric acid (SUA) is significantly elevated in obesity, gout, type 2 diabetes mellitus, and
the metabolic syndrome and appears to contribute to the renal, cardiovascular and …

Background: Altered intestinal function is prevalent in patients with heart failure (HF), but its
role in adverse outcomes is unclear. Objectives: This study investigated the potential …

Ganoderma lucidum polysaccharides (GLP), a kind of medicinal mushrooms, were widely
used in southeastern countries with putative anti-diabetic effects. In order to unravel the …

The intake of added sugars, such as from table sugar (sucrose) and high-fructose corn syrup
has increased dramatically in the last hundred years and correlates closely with the rise in …

High dietary fructose is a major contributor to insulin resistance and metabolic syndrome,
disturbing tissue and organ functions. Fructose is mainly absorbed into systemic circulation …

Patients with chronic kidney disease (CKD) are at a highly increased risk of cardiovascular
complications, with increased vascular inflammation, accelerated atherogenesis and …

Kidney damage represents a frequent event in the course of hypertension, ranging from a
benign to a malignant form of nephropathy depending on several factors, that is, individual …

Elevated serum uric acid concentration is a common laboratory finding in subjects with
metabolic syndrome/obesity, hypertension, kidney disease and cardiovascular events …