Engineering of BODIPY-based theranostics for cancer therapy

Z Mao, JH Kim, J Lee, H Xiong, F Zhang… - Coordination Chemistry …, 2023 - Elsevier
In recent years, BODIPY-based theranostics have increasingly been used in cancer therapy
and have achieved significant success. According to photochemical theories, the optical …

Emerging strategies in stimuli-responsive prodrug nanosystems for cancer therapy

C Ding, C Chen, X Zeng, H Chen, Y Zhao - ACS nano, 2022 - ACS Publications
Prodrugs are chemically modified drug molecules that are inactive before administration.
After administration, they are converted in situ to parent drugs and induce the mechanism of …

Tumor-generated reactive oxygen species storm for high-performance ferroptosis therapy

L Huang, J Zhu, W Xiong, J Feng, J Yang, X Lu, Y Lu… - ACS …, 2023 - ACS Publications
Ferroptosis therapy (FT) efficacy of tumors suffers from a relatively low concentration of
Fenton agents, limited hydrogen peroxide (H2O2) content, and insufficient acidity in the …

Nanoparticle‐mediated radiotherapy remodels the tumor microenvironment to enhance antitumor efficacy

W Zhen, RR Weichselbaum, W Lin - Advanced Materials, 2023 - Wiley Online Library
Radiotherapy (RT) uses ionizing radiation to eradicate localized tumors and, in rare cases,
control tumors outside of the irradiated fields via stimulating an antitumor immune response …

A Microenvironment Dual‐Responsive Nano‐Drug Equipped with PD‐L1 Blocking Peptide Triggers Immunogenic Pyroptosis for Prostate Cancer Self‐Synergistic …

H Wang, Z Gao, D Jiao, Y Zhang… - Advanced Functional …, 2023 - Wiley Online Library
Induction of immunogenic cell death (ICD) in tumor combined with immune checkpoint
blockade (ICB) therapy is widely developed to improve the efficacy of cancer …

Open‐shell nanosensitizers for glutathione responsive cancer sonodynamic therapy

H Wang, J Guo, W Lin, Z Fu, X Ji, B Yu, M Lu… - Advanced …, 2022 - Wiley Online Library
Deleterious effects to normal tissues and short biological half‐life of sonosensitizers limit the
applications of sonodynamic therapy (SDT). Herein, a new sonosensitizer (Cu (II) NS) is …

A vanadium-based nanoplatform synergizing ferroptotic-like therapy with glucose metabolism intervention for enhanced cancer cell death and antitumor immunity

Y Zhang, X Du, Z He, S Gao, L Ye, J Ji, X Yang… - ACS nano, 2023 - ACS Publications
Ferroptosis activation has been considered a mighty weapon for cancer treatment, and
growing attention is being paid to reinforcing tumor cells' sensitivity to ferroptosis. However …

[HTML][HTML] Targeting glucose metabolism enzymes in cancer treatment: current and emerging strategies

Y Zhang, Q Li, Z Huang, B Li, EC Nice, C Huang, L Wei… - Cancers, 2022 - mdpi.com
Simple Summary Reprogramming of glucose metabolism is a hallmark of cancer and can be
targeted by therapeutic agents. Some metabolism regulators, such as ivosidenib and …

Mitochondrial dysfunction-targeted nanosystems for precise tumor therapeutics

Z Ma, H Han, Y Zhao - Biomaterials, 2023 - Elsevier
Mitochondria play critical roles in the regulation of the proliferation and apoptosis of
cancerous cells. Targeted induction of mitochondrial dysfunction in cancer cells by …

Liquid nanoparticles for nanocatalytic cancer therapy

R Hu, X Chen, Z Li, G Zhao, L Ding, L Chen… - Advanced …, 2023 - Wiley Online Library
Nanotechnology is revolutionizing cancer therapy, and catalyzes the emerging of ion‐
involved cancer‐therapeutic modality, which unfortunately suffers from undesirable …