Engineering of BODIPY-based theranostics for cancer therapy
In recent years, BODIPY-based theranostics have increasingly been used in cancer therapy
and have achieved significant success. According to photochemical theories, the optical …
and have achieved significant success. According to photochemical theories, the optical …
Emerging strategies in stimuli-responsive prodrug nanosystems for cancer therapy
Prodrugs are chemically modified drug molecules that are inactive before administration.
After administration, they are converted in situ to parent drugs and induce the mechanism of …
After administration, they are converted in situ to parent drugs and induce the mechanism of …
Tumor-generated reactive oxygen species storm for high-performance ferroptosis therapy
Ferroptosis therapy (FT) efficacy of tumors suffers from a relatively low concentration of
Fenton agents, limited hydrogen peroxide (H2O2) content, and insufficient acidity in the …
Fenton agents, limited hydrogen peroxide (H2O2) content, and insufficient acidity in the …
Nanoparticle‐mediated radiotherapy remodels the tumor microenvironment to enhance antitumor efficacy
Radiotherapy (RT) uses ionizing radiation to eradicate localized tumors and, in rare cases,
control tumors outside of the irradiated fields via stimulating an antitumor immune response …
control tumors outside of the irradiated fields via stimulating an antitumor immune response …
A Microenvironment Dual‐Responsive Nano‐Drug Equipped with PD‐L1 Blocking Peptide Triggers Immunogenic Pyroptosis for Prostate Cancer Self‐Synergistic …
H Wang, Z Gao, D Jiao, Y Zhang… - Advanced Functional …, 2023 - Wiley Online Library
Induction of immunogenic cell death (ICD) in tumor combined with immune checkpoint
blockade (ICB) therapy is widely developed to improve the efficacy of cancer …
blockade (ICB) therapy is widely developed to improve the efficacy of cancer …
Open‐shell nanosensitizers for glutathione responsive cancer sonodynamic therapy
H Wang, J Guo, W Lin, Z Fu, X Ji, B Yu, M Lu… - Advanced …, 2022 - Wiley Online Library
Deleterious effects to normal tissues and short biological half‐life of sonosensitizers limit the
applications of sonodynamic therapy (SDT). Herein, a new sonosensitizer (Cu (II) NS) is …
applications of sonodynamic therapy (SDT). Herein, a new sonosensitizer (Cu (II) NS) is …
A vanadium-based nanoplatform synergizing ferroptotic-like therapy with glucose metabolism intervention for enhanced cancer cell death and antitumor immunity
Y Zhang, X Du, Z He, S Gao, L Ye, J Ji, X Yang… - ACS nano, 2023 - ACS Publications
Ferroptosis activation has been considered a mighty weapon for cancer treatment, and
growing attention is being paid to reinforcing tumor cells' sensitivity to ferroptosis. However …
growing attention is being paid to reinforcing tumor cells' sensitivity to ferroptosis. However …
[HTML][HTML] Targeting glucose metabolism enzymes in cancer treatment: current and emerging strategies
Simple Summary Reprogramming of glucose metabolism is a hallmark of cancer and can be
targeted by therapeutic agents. Some metabolism regulators, such as ivosidenib and …
targeted by therapeutic agents. Some metabolism regulators, such as ivosidenib and …
Mitochondrial dysfunction-targeted nanosystems for precise tumor therapeutics
Mitochondria play critical roles in the regulation of the proliferation and apoptosis of
cancerous cells. Targeted induction of mitochondrial dysfunction in cancer cells by …
cancerous cells. Targeted induction of mitochondrial dysfunction in cancer cells by …
Liquid nanoparticles for nanocatalytic cancer therapy
Nanotechnology is revolutionizing cancer therapy, and catalyzes the emerging of ion‐
involved cancer‐therapeutic modality, which unfortunately suffers from undesirable …
involved cancer‐therapeutic modality, which unfortunately suffers from undesirable …