[HTML][HTML] CD4+ T cell memory
M Künzli, D Masopust - Nature immunology, 2023 - nature.com
Specialized subpopulations of CD4+ T cells survey major histocompatibility complex class II–
peptide complexes to control phagosomal infections, help B cells, regulate tissue …
peptide complexes to control phagosomal infections, help B cells, regulate tissue …
Viral vectored vaccines: design, development, preventive and therapeutic applications in human diseases
S Wang, B Liang, W Wang, L Li, N Feng… - Signal transduction and …, 2023 - nature.com
Human diseases, particularly infectious diseases and cancers, pose unprecedented
challenges to public health security and the global economy. The development and …
challenges to public health security and the global economy. The development and …
Imprinted antibody responses against SARS-CoV-2 Omicron sublineages
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages carry
distinct spike mutations resulting in escape from antibodies induced by previous infection or …
distinct spike mutations resulting in escape from antibodies induced by previous infection or …
Omicron spike function and neutralizing activity elicited by a comprehensive panel of vaccines
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of
concern comprises several sublineages, with BA. 2 and BA. 2.12. 1 having replaced the …
concern comprises several sublineages, with BA. 2 and BA. 2.12. 1 having replaced the …
Unadjuvanted intranasal spike vaccine elicits protective mucosal immunity against sarbecoviruses
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
highlighted the need for vaccines that not only prevent disease but also prevent …
highlighted the need for vaccines that not only prevent disease but also prevent …
[HTML][HTML] Humoral and cellular immune memory to four COVID-19 vaccines
Multiple COVID-19 vaccines, representing diverse vaccine platforms, successfully protect
against symptomatic COVID-19 cases and deaths. Head-to-head comparisons of T cell, B …
against symptomatic COVID-19 cases and deaths. Head-to-head comparisons of T cell, B …
Polymer nanoparticles deliver mRNA to the lung for mucosal vaccination
An inhalable platform for messenger RNA (mRNA) therapeutics would enable minimally
invasive and lung-targeted delivery for a host of pulmonary diseases. Development of lung …
invasive and lung-targeted delivery for a host of pulmonary diseases. Development of lung …
Respiratory mucosal immune memory to SARS-CoV-2 after infection and vaccination
Respiratory mucosal immunity induced by vaccination is vital for protection from coronavirus
infection in animal models. In humans, the capacity of peripheral vaccination to generate …
infection in animal models. In humans, the capacity of peripheral vaccination to generate …
[HTML][HTML] Secondary influenza challenge triggers resident memory B cell migration and rapid relocation to boost antibody secretion at infected sites
Resident memory B (BRM) cells develop and persist in the lungs of influenza-infected mice
and humans; however, their contribution to recall responses has not been defined. Here, we …
and humans; however, their contribution to recall responses has not been defined. Here, we …
Influenza vaccine format mediates distinct cellular and antibody responses in human immune organoids
JM Kastenschmidt, S Sureshchandra, A Jain… - Immunity, 2023 - cell.com
Highly effective vaccines elicit specific, robust, and durable adaptive immune responses. To
advance informed vaccine design, it is critical that we understand the cellular dynamics …
advance informed vaccine design, it is critical that we understand the cellular dynamics …