Endothelial monocyte-activating polypeptide-ii is an indicator of severity and mortality in COVID-19 patients
Data for predicting the severity and mortality of coronavirus disease 2019 (COVID-19) are
limited, and investigations are ongoing. Endothelial monocyte-activating protein II (EMAP-II) …
limited, and investigations are ongoing. Endothelial monocyte-activating protein II (EMAP-II) …
Subcutaneous administration of neutralizing antibodies to endothelial monocyte-activating protein II attenuates cigarette smoke-induced lung injury in mice
K Koike, EL Beatman, KS Schweitzer… - … of Physiology-Lung …, 2019 - journals.physiology.org
Proapoptotic and monocyte chemotactic endothelial monocyte-activating protein 2 (EMAPII)
is released extracellularly during cigarette smoke (CS) exposure. We have previously …
is released extracellularly during cigarette smoke (CS) exposure. We have previously …
Endothelial-monocyte activating polypeptide II disrupts alveolar epithelial type II to type I cell transdifferentiation
Y Chen, SK Legan, A Mahan, J Thornton, H Xu… - Respiratory …, 2012 - Springer
Background Distal alveolar morphogenesis is marked by differentiation of alveolar type (AT)-
II to AT-I cells that give rise to the primary site of gas exchange, the alveolar/vascular …
II to AT-I cells that give rise to the primary site of gas exchange, the alveolar/vascular …
[HTML][HTML] IGSF3 mutation identified in patient with severe COPD alters cell function and motility
Cigarette smoking (CS) and genetic susceptibility determine the risk for development,
progression, and severity of chronic obstructive pulmonary diseases (COPD). We posited …
progression, and severity of chronic obstructive pulmonary diseases (COPD). We posited …
A distinct transcriptional profile in response to endothelial monocyte activating polypeptide II is partially mediated by JAK-STAT3 in murine macrophages
DD Lee, A Hochstetler, C Murphy… - … of Physiology-Cell …, 2019 - journals.physiology.org
Macrophages are important responders to environmental changes such as secreted factors.
Among the secreted factors in injured tissues, the highly conserved endothelial monocyte …
Among the secreted factors in injured tissues, the highly conserved endothelial monocyte …
Novel imaging approaches for small animal models of lung disease (2017 Grover Conference series)
IP Pinar, HD Jones - Pulmonary Circulation, 2018 - journals.sagepub.com
Imaging in small animal models of lung disease is challenging, as existing technologies are
limited either by resolution or by the terminal nature of the imaging approach. Here, we …
limited either by resolution or by the terminal nature of the imaging approach. Here, we …
[HTML][HTML] Nonclassically secreted regulators of angiogenesis
I Prudovsky - Angiology: open access, 2013 - ncbi.nlm.nih.gov
Many secreted polypeptide regulators of angiogenesis are devoid of signal peptides. These
proteins are released through nonclassical pathways independent of endoplasmic reticulum …
proteins are released through nonclassical pathways independent of endoplasmic reticulum …
Cell proliferation and migration are modulated by Cdk-1-phosphorylated endothelial-monocyte activating polypeptide II
Background Endothelial-Monocyte Activating Polypeptide (EMAP II) is a secreted protein
with well-established anti-angiogenic activities. Intracellular EMAP II expression is increased …
with well-established anti-angiogenic activities. Intracellular EMAP II expression is increased …
[PDF][PDF] Pulmonary hypertension precedes emphysema: paradigm shift or artifact of rodent studies
Chronic Obstructive Pulmonary Disease (COPD) is often oversimplified as it was just chronic
bronchitis. The patient is such depicted as a constantly coughing and heavily breathing …
bronchitis. The patient is such depicted as a constantly coughing and heavily breathing …