Adapting to obesity with adipose tissue inflammation
SM Reilly, AR Saltiel - Nature Reviews Endocrinology, 2017 - nature.com
Adipose tissue not only has an important role in the storage of excess nutrients but also
senses nutrient status and regulates energy mobilization. An overall positive energy balance …
senses nutrient status and regulates energy mobilization. An overall positive energy balance …
[HTML][HTML] Contribution of adipose tissue inflammation to the development of type 2 diabetes mellitus
MS Burhans, DK Hagman, JN Kuzma… - Comprehensive …, 2018 - ncbi.nlm.nih.gov
The objective of this comprehensive review is to summarize and discuss the available
evidence of how adipose tissue inflammation affects insulin sensitivity and glucose …
evidence of how adipose tissue inflammation affects insulin sensitivity and glucose …
[HTML][HTML] Multifactorial mechanism of sarcopenia and sarcopenic obesity. Role of physical exercise, microbiota and myokines
J Bilski, P Pierzchalski, M Szczepanik, J Bonior… - Cells, 2022 - mdpi.com
Obesity and ageing place a tremendous strain on the global healthcare system. Age-related
sarcopenia is characterized by decreased muscular strength, decreased muscle quantity …
sarcopenia is characterized by decreased muscular strength, decreased muscle quantity …
Mechanisms of muscle insulin resistance and the cross‐talk with liver and adipose tissue
SC da Silva Rosa, N Nayak, AM Caymo… - Physiological …, 2020 - Wiley Online Library
Insulin resistance is a metabolic disorder affecting multiple tissues and is a precursor event
to type 2 diabetes (T2D). As T2D affects over 425 million people globally, there is an …
to type 2 diabetes (T2D). As T2D affects over 425 million people globally, there is an …
[HTML][HTML] Crosstalk between gut microbiota and dietary lipids aggravates WAT inflammation through TLR signaling
R Caesar, V Tremaroli, P Kovatcheva-Datchary… - Cell metabolism, 2015 - cell.com
Dietary lipids may influence the abundance of circulating inflammatory microbial factors.
Hence, inflammation in white adipose tissue (WAT) induced by dietary lipids may be partly …
Hence, inflammation in white adipose tissue (WAT) induced by dietary lipids may be partly …
Obesity and inflammation
J Karczewski, E Śledzińska, A Baturo, I Jończyk… - European cytokine …, 2018 - Springer
The prevalence of obesity has recently increased dramatically and has contributed to the
increasing prevalence of various pathological conditions, including type 2 diabetes mellitus …
increasing prevalence of various pathological conditions, including type 2 diabetes mellitus …
Self-regulation and cross-regulation of pattern-recognition receptor signalling in health and disease
X Cao - Nature Reviews Immunology, 2016 - nature.com
In the initiation of innate immune responses against pathogens, pattern-recognition
receptors (PRRs) have an essential role in recognizing specific components of …
receptors (PRRs) have an essential role in recognizing specific components of …
Saturated fatty acids trigger TLR4-mediated inflammatory response
DM Rocha, AP Caldas, LL Oliveira, J Bressan… - Atherosclerosis, 2016 - Elsevier
Toll-like receptors (TLR) mediate infection-induced inflammation and sterile inflammation by
endogenous molecules. Among the TLR family, TLR4 is the best understood. However …
endogenous molecules. Among the TLR family, TLR4 is the best understood. However …
[HTML][HTML] Moderate dietary protein restriction alters the composition of gut microbiota and improves ileal barrier function in adult pig model
This study was conducted to investigate impacts of dietary protein levels on gut bacterial
community and gut barrier. The intestinal microbiota of finishing pigs, fed with 16%, 13% and …
community and gut barrier. The intestinal microbiota of finishing pigs, fed with 16%, 13% and …
Role of adipose tissue macrophages in obesity-related disorders
The obesity epidemic has led researchers and clinicians to reconsider the etiology of this
disease and precisely decipher its molecular mechanisms. The excessive accumulation of …
disease and precisely decipher its molecular mechanisms. The excessive accumulation of …