Conditioned place preference (CPP) continues to be one of the most popular models to
study the motivational effects of drugs and non‐drug treatments in experimental animals …

In this review we will critically assess the hypothesis that the reinforcing effect of virtually all
drugs of abuse is primarily dependent on activation of the mesolimbic dopamine system …

Dr. Jacqueline N. Crawley, author of the First and Second Editions of What's Wrong with My
Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice, continues to field calls …

During the last few years, the endocannabinoid system has emerged as a highly relevant
topic in the scientific community. Many different regulatory actions have been attributed to …

The discovery that the adult mammalian brain creates new neurons from pools of stemlike
cells was a breakthrough in neuroscience. Interestingly, this particular new form of structural …

Biphasic effects of cannabinoids have been shown in processes such as feeding behavior,
motor activity, motivational processes and anxiety responses. Using two different tests for the …

Drug Addiction | New England Journal of Medicine Skip to main content The New England
Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …

K2 or Spice products are emerging drugs of abuse that contain synthetic cannabinoids
(SCBs). Although assumed by many teens and first time drug users to be a “safe” and “legal” …

The endogenous cannabinoid system is an ubiquitous lipid signalling system that appeared
early in evolution and which has important regulatory functions throughout the body in all …

Recent studies have shown that the endocannabinoid system is involved in the common
neurobiological mechanism underlying drug addiction. This system participates in the …