Background. Adolescent anemia is a major public health problem worldwide. Adolescents
(10–19 years) are at an increased risk of developing anemia due to increased iron demand …

Iron is needed for life‐essential processes, but free iron overload causes dangerous clinical
consequences. The study of the role of red blood cells (RBCs) in the influence of excess free …

Thalassemia is a chronic disease caused by impaired globin chain synthesis, leading to
ineffective erythropoiesis, hemolysis, and chronic anemia. The treatment of patients with …

Thalassemia major is the most common monogenetic disorder worldwide, manifested as
chronic hemolytic anemia. This condition leads to the need for chronic blood transfusion to …

Introduction Lead poisoning contributes to a significant burden of disease as a toxic
substance found in air, soil, and water. In Indonesia, the risk of exposure is high due to the …

Abstract Introduction Major Thalassemia patients suffer from iron overload and organ
damage, especially heart and liver damage. Early diagnosis and treatment with a chelator …

Background: Cardiac complications in patients with transfusion-dependent thalassemia
(TDT) are one of the ma-jor causes of mortality in these patients which annually impose …

Introduction: Ferritin is a routine parameter used in the evaluation of iron overload in
thalassemia patients. Excess iron causes the formation of ROS, resulting in an oxidative …

Objective: To determine the molecular characterisation of beta-thalassemia major patients,
pattern of major endocrine complications and its association with haemoglobin subunit beta …

Beta thalassemia is one of the most common hereditary diseases in the world caused by a
deficiency of globin chains. Heart disease is one of the main complications of this disease as …