Electrospun fibers control drug delivery for tissue regeneration and cancer therapy
L Li, R Hao, J Qin, J Song, X Chen, F Rao, J Zhai… - Advanced Fiber …, 2022 - Springer
Versatile strategies have been developed to construct electrospun fiber-based drug delivery
systems for tissue regeneration and cancer therapy. We first introduce the construction of …
systems for tissue regeneration and cancer therapy. We first introduce the construction of …
[HTML][HTML] 3D bioprinting: a novel avenue for manufacturing tissues and organs
Abstract Three-dimensional (3D) bioprinting is a rapidly growing technology that has been
widely used in tissue engineering, disease studies, and drug screening. It provides the …
widely used in tissue engineering, disease studies, and drug screening. It provides the …
Minimally invasive delivery of therapeutic agents by hydrogel injection into the pericardial cavity for cardiac repair
Cardiac patches are an effective way to deliver therapeutics to the heart. However, such
procedures are normally invasive and difficult to perform. Here, we develop and test a …
procedures are normally invasive and difficult to perform. Here, we develop and test a …
Programming cellular alignment in engineered cardiac tissue via bioprinting anisotropic organ building blocks
The ability to replicate the 3D myocardial architecture found in human hearts is a grand
challenge. Here, the fabrication of aligned cardiac tissues via bioprinting anisotropic organ …
challenge. Here, the fabrication of aligned cardiac tissues via bioprinting anisotropic organ …
4D physiologically adaptable cardiac patch: A 4-month in vivo study for the treatment of myocardial infarction
H Cui, C Liu, T Esworthy, Y Huang, Z Yu, X Zhou… - Science …, 2020 - science.org
There has been considerable progress in engineering cardiac scaffolds for the treatment of
myocardial infarction (MI). However, it is still challenging to replicate the structural specificity …
myocardial infarction (MI). However, it is still challenging to replicate the structural specificity …
A minimally invasive exosome spray repairs heart after myocardial infarction
Myocardial infarction (MI) remains the most common cause of death worldwide. Many MI
survivors will suffer from recurrent heart failure (HF), which has been recognized as a …
survivors will suffer from recurrent heart failure (HF), which has been recognized as a …
Human engineered heart tissue patches remuscularize the injured heart in a dose-dependent manner
E Querdel, M Reinsch, L Castro, D Köse, A Bähr… - Circulation, 2021 - Am Heart Assoc
Background: Human engineered heart tissue (EHT) transplantation represents a potential
regenerative strategy for patients with heart failure and has been successful in preclinical …
regenerative strategy for patients with heart failure and has been successful in preclinical …
Nanowired human cardiac organoid transplantation enables highly efficient and effective recovery of infarcted hearts
Human cardiac organoids hold remarkable potential for cardiovascular disease modeling
and human pluripotent stem cell–derived cardiomyocyte (hPSC-CM) transplantation. Here …
and human pluripotent stem cell–derived cardiomyocyte (hPSC-CM) transplantation. Here …
An intrapericardial injectable hydrogel patch for mechanical–electrical coupling with infarcted myocardium
Although hydrogel-based patches have shown promising therapeutic efficacy in myocardial
infarction (MI), synergistic mechanical, electrical, and biological cues are required to restore …
infarction (MI), synergistic mechanical, electrical, and biological cues are required to restore …
A Bi‐Layer Hydrogel Cardiac Patch Made of Recombinant Functional Proteins
X Jiang, T Feng, B An, S Ren, J Meng, K Li… - Advanced …, 2022 - Wiley Online Library
The development of minimally invasive cardiac patches, either as hemostatic dressing or
treating myocardial infarction, is of clinical significance but remains a major challenge …
treating myocardial infarction, is of clinical significance but remains a major challenge …