A Bi‐Layer Hydrogel Cardiac Patch Made of Recombinant Functional Proteins

X Jiang, T Feng, B An, S Ren, J Meng, K Li… - Advanced …, 2022 - Wiley Online Library
The development of minimally invasive cardiac patches, either as hemostatic dressing or
treating myocardial infarction, is of clinical significance but remains a major challenge …

A framework for developing sex-specific engineered heart models

R Lock, H Al Asafen, S Fleischer, M Tamargo… - Nature Reviews …, 2022 - nature.com
The convergence of tissue engineering and patient-specific stem cell biology has enabled
the engineering of in vitro tissue models that allow the study of patient-tailored treatment …

Harnessing organs-on-a-chip to model tissue regeneration

DN Tavakol, S Fleischer, G Vunjak-Novakovic - Cell Stem Cell, 2021 - cell.com
Tissue engineering has markedly matured since its early beginnings in the 1980s. In
addition to the original goal to regenerate damaged organs, the field has started to explore …

Bioresorbable polymeric scaffold in cardiovascular applications

DWY Toong, HW Toh, JCK Ng, PEH Wong… - International journal of …, 2020 - mdpi.com
Advances in material science and innovative medical technologies have allowed the
development of less invasive interventional procedures for deploying implant devices …

The role of Hydrogel in Cardiac Repair and Regeneration for myocardial infarction: recent advances and future perspectives

P Li, J Hu, J Wang, J Zhang, L Wang, C Zhang - Bioengineering, 2023 - mdpi.com
A myocardial infarction (MI) is the leading cause of morbidity and mortality, seriously
threatens human health, and becomes a major health burden of our society. It is urgent to …

Generation of endothelial cells from human pluripotent stem cells: methods, considerations, and applications

IM Williams, JC Wu - Arteriosclerosis, thrombosis, and vascular …, 2019 - Am Heart Assoc
Endothelial cells (ECs) are critical for several aspects of cardiovascular disease therapy,
including vascular regeneration, personalized drug development, and tissue engineering …

Cells, materials, and fabrication processes for cardiac tissue engineering

P Montero, M Flandes-Iparraguirre… - … in Bioengineering and …, 2020 - frontiersin.org
Cardiovascular disease is the number one killer worldwide, with myocardial infarction (MI)
responsible for approximately 1 in 6 deaths. The lack of endogenous regenerative capacity …

Engineering multifunctional dynamic hydrogel for biomedical and tissue regenerative applications

B Yin, M Gosecka, M Bodaghi, D Crespy… - Chemical Engineering …, 2024 - Elsevier
Hydrogels have emerged in various biomedical applications, including tissue engineering
and medical devices, due to their ability to imitate the natural extracellular matrix (ECM) of …

Sustained release of bioactive IGF-1 from a silk fibroin microsphere-based injectable alginate hydrogel for the treatment of myocardial infarction

J Feng, Y Wu, W Chen, J Li, X Wang, Y Chen… - Journal of Materials …, 2020 - pubs.rsc.org
Low circulating levels of insulin-like growth factor 1 (IGF-1) have been correlated with an
increased risk for cardiovascular diseases in humans. In this work, an injectable alginate …

[HTML][HTML] Porous scaffold for mesenchymal cell encapsulation and exosome-based therapy of ischemic diseases

A Czosseck, MM Chen, H Nguyen, A Meeson… - Journal of Controlled …, 2022 - Elsevier
Ischemic diseases including myocardial infarction (MI) and limb ischemia are some of the
greatest causes of morbidity and mortality worldwide. Cell therapy is a potential treatment …