Exosomes, mainly derived from mesenchymal stem cells, provide a good reference for
cardiac function repair and clinical application in cardiac and vascular diseases by …

Despite a massive global preventative effort, heart failure remains the major cause of death
globally. The number of patients requiring a heart transplant, the eventual last treatment …

In this study, we investigated whether human umbilical cord mesenchymal stem cell
(hUCMSC) fibrin patches loaded with nerve growth factor (NGF) poly (lactic-co-glycolic …

Despite several advances in cardiac tissue engineering, one of the major challenges to
overcome remains the generation of a fully functional vascular network comprising several …

Background To treat chronic heart failure (CHF), we developed a robust, easy to handle
bioabsorbable tissue-engineered patch embedded with human neonatal fibroblasts and …

Cardiovascular diseases, including myocardial infarction (MI), persist as the leading cause
of mortality and morbidity worldwide. The limited regenerative capacity of the myocardium …

The engineered myocardial tissues produced via most manufacturing techniques are
typically just a few dozen micrometers thick, which is too thin for therapeutic applications in …

Cardiovascular disease is the leading cause of death in the United States, which can result
in blockage of a coronary artery, triggering a myocardial infarction (MI), scar tissue formation …

Heart failure (HF) is one of the most important cardiovascular diseases (CVD), causing many
die every year. Cardiac tissue engineering is a multidisciplinary field for creating functional …

Objective: After acute myocardial infarction (AMI), the loss of cardiomyocytes and
dysregulation of extracellular matrix homeostasis results in impaired cardiac function and …