Objectives Interictal epileptiform discharges (IED s) have been linked to memory impairment,
but the spatial and temporal dynamics of this relationship remain elusive. In the present …

Responsive neurostimulation (RNS) has recently emerged as a safe and effective treatment
for some patients with medically refractory focal epilepsy who are not candidates for surgical …

The cyclical organization of seizures in epilepsy has been described since antiquity.
However, historical explanations for seizure cycles—based on celestial, hormonal, and …

Objective Interictal spikes help localize seizure generators as part of surgical planning for
drug‐resistant epilepsy. However, there are often multiple spike populations whose …

The current paradigm for treatment of epilepsy begins with trials of antiepileptic drugs,
followed by evaluation for resective brain surgery in drug-resistant patients. If surgery is not …

Abstract Background In patients with Alzheimer's disease (AD) without clinical seizures, up
to half have epileptiform discharges on long-term in-patient electroencephalography (EEG) …

There is an ongoing debate whether generic early warning signals for critical transitions
exist that can be applied across diverse systems. The human epileptic brain is often …

Objective Develop a high-performing algorithm to detect mesial temporal lobe (mTL)
epileptiform discharges on intracranial electrode recordings. Methods An epileptologist …

Objective Ear-EEG is recording of electroencephalography from a small device in the ear.
This is the first study to compare ictal and interictal abnormalities recorded with ear-EEG and …

Epilepsy is one of the most common neurological disorders, and it affects almost 1% of the
population worldwide. Many people living with epilepsy continue to have seizures despite …