It remains unclear to what extent neurodevelopmental disorder (NDD) risk genes retain
functions into adulthood and how they may influence disease phenotypes. SYNGAP1 …

Objective Sleep has important influences on focal interictal epileptiform discharges (IEDs),
and the rates and spatial extent of IEDs are increased in non‐rapid eye movement (NREM) …

Brain-state transitions are readily apparent from changes in brain rhythms, but are difficult to
predict, suggestive that the underlying cause is latent to passive recording methods. Among …

Epileptic activity without visible convulsions is common in Alzheimer's disease (AD) and may
contribute adversely to the disease progress and symptoms. Transgenic mice with amyloid …

Early implantable epilepsy therapy devices provided open-loop electrical stimulation without
brain sensing, computing, or an interface for synchronized behavioural inputs from patients …

Seizures beget seizures is a longstanding theory that proposed that seizure activity can
impact the structural and functional properties of the brain circuits in ways that contribute to …

Sleep and wake are defined through physiological and behavioral criteria and can be
typically separated into non‐rapid eye movement (NREM) sleep stages N1, N2, and N3 …

The latency between traumatic brain injury (TBI) and the onset of epilepsy (PTE) represents
an opportunity for counteracting epileptogenesis. Antiepileptogenesis trials are hampered …

Objective Epilepsy is characterized by spontaneous seizures that recur at unexpected times.
Nonetheless, using years‐long electroencephalographic (EEG) recordings, we previously …

Seizure detection, and more recently seizure forecasting, represent important avenues of
clinical development in epilepsy, promoted by progress in wearable devices and mobile …