Measurement of polycyclic aromatic hydrocarbons (PAH) metabolites in human urine is the
method of choice to determine occupational and/or environmental exposure of an individual …

Recent molecular epidemiologic research provides compelling new evidence that
environmental factors are major contributors to human cancer and that their risks are …

Publisher Summary Chemical carcinogenesis research has substantially broadened the
understanding of the cellular and molecular changes involved in cancer development and …

Polycyclic Aromatic Hydrocarbons (PAHs) are a group of chemicals that are formed during
the incomplete burning of coal, oil, gas, wood, garbage, or other organic substances, such …

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous carcinogenic substances to which
man is exposed in the environment and at certain workplaces. Estimation of the resulting …

Biological markers, or biomarkers, reflect molecular and cellular alterations that occur along
the temporal and mechanistic pathways connecting exposure to toxic chemicals or physical …

The presence of covalent DNA chemical addition products (adducts) in human term
placentas was investigated by recently developed immunologic and 32P-postlabeling …

The demonstration in the mid-1960s and early 1970s that antibodies could be generated
against the normal nucleosides suggested that antibodies to modified nucleosides were …

Most people in the United States spend far more time indoors than outdoors. Yet, many air
pollution regulations and risk assessments focus on outdoor air. These often overlook …

The possibilities and limitations of using mercapturic acids and protein and DNA adducts for
the assessment of internal and effective doses of electrophilic chemicals are reviewed …