Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases

AB Kunnumakkara, D Bordoloi… - British journal of …, 2017 - Wiley Online Library
Curcumin, a yellow pigment in the Indian spice Turmeric (Curcuma longa), which is
chemically known as diferuloylmethane, was first isolated exactly two centuries ago in 1815 …

Role of turmeric and curcumin in prevention and treatment of chronic diseases: Lessons learned from clinical trials

AB Kunnumakkara, M Hegde, D Parama… - ACS Pharmacology & …, 2023 - ACS Publications
Turmeric (Curcuma longa) has been used for thousands of years for the prevention and
treatment of various chronic diseases. Curcumin is just one of> 200 ingredients in turmeric …

Promising natural products in new drug design, development, and therapy for skin disorders: An overview of scientific evidence and understanding their mechanism of …

NA Mohd Zaid, M Sekar, SR Bonam… - Drug design …, 2023 - Taylor & Francis
The skin is the largest organ in the human body, composed of the epidermis and the dermis.
It provides protection and acts as a barrier against external menaces like allergens …

A review of therapeutic potentials of turmeric (Curcuma longa) and its active constituent, curcumin, on inflammatory disorders, pain, and their related patents

BM Razavi, M Ghasemzadeh Rahbardar… - Phytotherapy …, 2021 - Wiley Online Library
Turmeric (Curcuma longa) and its constituent, curcumin, have been used for their
therapeutic properties for a long time. Most of the medicinal impacts of turmeric and …

Bactericidal activity of curcumin I is associated with damaging of bacterial membrane

P Tyagi, M Singh, H Kumari, A Kumari… - PloS one, 2015 - journals.plos.org
Curcumin, an important constituent of turmeric, is known for various biological activities,
primarily due to its antioxidant mechanism. The present study focused on the antibacterial …

Amyloid β oligomers in Alzheimer's disease pathogenesis, treatment, and diagnosis

KL Viola, WL Klein - Acta neuropathologica, 2015 - Springer
Protein aggregation is common to dozens of diseases including prionoses, diabetes,
Parkinson's and Alzheimer's. Over the past 15 years, there has been a paradigm shift in …

Diet as a trigger or therapy for inflammatory bowel diseases

JD Lewis, MT Abreu - Gastroenterology, 2017 - Elsevier
The most common question asked by patients with inflammatory bowel disease (IBD)
is,“Doctor, what should I eat?” Findings from epidemiology studies have indicated that diets …

Potential of curcumin in skin disorders

L Vollono, M Falconi, R Gaziano, F Iacovelli, E Dika… - Nutrients, 2019 - mdpi.com
Curcumin is a compound isolated from turmeric, a plant known for its medicinal use.
Recently, there is a growing interest in the medical community in identifying novel, low-cost …

[HTML][HTML] Broad targeting of angiogenesis for cancer prevention and therapy

Z Wang, C Dabrosin, X Yin, MM Fuster, A Arreola… - Seminars in cancer …, 2015 - Elsevier
Deregulation of angiogenesis–the growth of new blood vessels from an existing vasculature–
is a main driving force in many severe human diseases including cancer. As such, tumor …

Curcumin, inflammation, and chronic diseases: how are they linked?

Y He, Y Yue, X Zheng, K Zhang, S Chen, Z Du - Molecules, 2015 - mdpi.com
It is extensively verified that continued oxidative stress and oxidative damage may lead to
chronic inflammation, which in turn can mediate most chronic diseases including cancer …