Strategies for non-viral vectors targeting organs beyond the liver
In recent years, nanoparticles have evolved to a clinical modality to deliver diverse nucleic
acids. Rising interest in nanomedicines comes from proven safety and efficacy profiles …
acids. Rising interest in nanomedicines comes from proven safety and efficacy profiles …
Advances in development of exosomes for ophthalmic therapeutics
Y Tian, T Zhang, J Li, Y Tao - Advanced Drug Delivery Reviews, 2023 - Elsevier
Exosomes contain multiple bioactive molecules and maintain the connection between cells.
Recent advances in exosome-based therapeutics have witnessed unprecedented …
Recent advances in exosome-based therapeutics have witnessed unprecedented …
[HTML][HTML] Stem cell sources and characterization in the development of cell-based products for treating retinal disease: An NEI Town Hall report
AM Fortress, KJ Miyagishima, AA Reed… - Stem cell research & …, 2023 - Springer
Abstract National Eye Institute recently issued a new Strategic Plan outlining priority
research areas for the next 5 years. Starting cell source for deriving stem cell lines is as an …
research areas for the next 5 years. Starting cell source for deriving stem cell lines is as an …
From biological aging to functional decline: A narrative review of insights into chronic inflammation and intrinsic capacity
X Li, L Ma - Ageing Research Reviews, 2023 - Elsevier
Intrinsic capacity is the sum of an individual's physical and mental capacities, which helps
determine functional ability. Intrinsic capacity decline is an important predictor of adverse …
determine functional ability. Intrinsic capacity decline is an important predictor of adverse …
[HTML][HTML] An Explainable Artificial Intelligence-Based Robustness Optimization Approach for Age-Related Macular Degeneration Detection Based on Medical IOT …
AI-based models have shown promising results in diagnosing eye diseases based on multi-
sources of data collected from medical IOT systems. However, there are concerns regarding …
sources of data collected from medical IOT systems. However, there are concerns regarding …
[HTML][HTML] Faricimab for the treatment of diabetic macular edema and neovascular age-related macular degeneration
Nowadays; intravitreal anti-vascular endothelial growth factor (VEGF) drugs are considered
the first-line therapeutic strategy for treating macular exudative diseases; including wet age …
the first-line therapeutic strategy for treating macular exudative diseases; including wet age …
[HTML][HTML] Preclinical investigations on broccoli-derived sulforaphane for the treatment of ophthalmic disease
Vision loss causes a significant burden on individuals and communities on a financial,
emotional and social level. Common causes include age-related macular degeneration …
emotional and social level. Common causes include age-related macular degeneration …
[HTML][HTML] Predicting late-stage age-related macular degeneration by integrating marginally weak SNPs in GWA studies
Introduction: Age-related macular degeneration (AMD) is a progressive neurodegenerative
disease and the leading cause of blindness in developed countries. Current genome-wide …
disease and the leading cause of blindness in developed countries. Current genome-wide …
[HTML][HTML] Microbiota mitochondria disorders as hubs for early age-related macular degeneration
Age-related macular degeneration (AMD) is a progressive neurodegenerative disease
affecting the central area (macula lutea) of the retina. Research on the pathogenic …
affecting the central area (macula lutea) of the retina. Research on the pathogenic …
[HTML][HTML] Association between age-related macular degeneration and the risk of diabetes mellitus: A nationwide cohort study
Age-related macular degeneration (AMD) is a degenerative and progressive disease of the
macula, the part of the retina that is responsible for central vision. AMD shares some risk …
macula, the part of the retina that is responsible for central vision. AMD shares some risk …