Is early-onset cancer an emerging global epidemic? Current evidence and future implications

T Ugai, N Sasamoto, HY Lee, M Ando… - Nature Reviews …, 2022 - nature.com
Over the past several decades, the incidence of early-onset cancers, often defined as
cancers diagnosed in adults< 50 years of age, in the breast, colorectum, endometrium …

Sex disparities matter in cancer development and therapy

S Haupt, F Caramia, SL Klein, JB Rubin… - Nature Reviews …, 2021 - nature.com
Curing cancer through precision medicine is the paramount aim of the new wave of
molecular and genomic therapies. Currently, whether patients with non-reproductive …

[HTML][HTML] Crosstalk between circRNAs and the PI3K/AKT signaling pathway in cancer progression

C Xue, G Li, J Lu, L Li - Signal transduction and targeted therapy, 2021 - nature.com
Circular RNAs (circRNAs), covalently closed noncoding RNAs, are widely expressed in
eukaryotes and viruses. They can function by regulating target gene expression, linear RNA …

Assessment and treatment of thyroid disorders in pregnancy and the postpartum period

SY Lee, EN Pearce - Nature Reviews Endocrinology, 2022 - nature.com
Thyroid disorders are prevalent in pregnant women. Furthermore, thyroid hormone has a
critical role in fetal development and thyroid dysfunction can adversely affect obstetric …

The epidemiological landscape of thyroid cancer worldwide: GLOBOCAN estimates for incidence and mortality rates in 2020

M Pizzato, M Li, J Vignat, M Laversanne… - The lancet Diabetes & …, 2022 - thelancet.com
Background Thyroid cancer incidence rates have increased in many countries and settings;
however, mortality rates have remained stable at lower rates. This epidemiological pattern …

Thyroid cancer: incidence and mortality trends in China, 2005–2015

J Wang, F Yu, Y Shang, Z Ping, L Liu - Endocrine, 2020 - Springer
Purpose Understanding secular trends of thyroid cancer is critical to plan strategies for
cancer prevention and control. Our aim was to estimate the incidence and mortality trends of …

[HTML][HTML] Thyroid nodules: Global, economic, and personal burdens

N Uppal, R Collins, B James - Frontiers in Endocrinology, 2023 - frontiersin.org
Thyroid nodules have garnered attention due to changes in population surveillance systems
and rising concerns about the associated financial burden on healthcare systems, payers …

[HTML][HTML] Malignancy rates in thyroid nodules: a long-term cohort study of 17,592 patients

M Grussendorf, I Ruschenburg… - European Thyroid …, 2022 - etj.bioscientifica.com
Objectives Ultrasound diagnosis of thyroid nodules has greatly increased their detection
rate. Their risk for malignancy is estimated between 7 and 15% in data from specialized …

[HTML][HTML] Multi-channel convolutional neural network architectures for thyroid cancer detection

X Zhang, VCS Lee, J Rong, F Liu, H Kong - Plos one, 2022 - journals.plos.org
Early detection of malignant thyroid nodules leading to patient-specific treatments can
reduce morbidity and mortality rates. Currently, thyroid specialists use medical images to …

A super-resolution guided network for improving automated thyroid nodule segmentation

X Lin, X Zhou, T Tong, X Nie, L Wang, H Zheng… - Computer Methods and …, 2022 - Elsevier
Background and Objective: A thyroid nodule is an abnormal lump that grows in the thyroid
gland, which is the early symptom of thyroid cancer. In order to diagnose and treat thyroid …