Long-term stability of cortical ensembles

J Pérez-Ortega, T Alejandre-García, R Yuste - Elife, 2021 - elifesciences.org
Neuronal ensembles, coactive groups of neurons found in spontaneous and evoked cortical
activity, are causally related to memories and perception, but it is still unknown how stable or …

Contribution of behavioural variability to representational drift

S Sadeh, C Clopath - Elife, 2022 - elifesciences.org
Neuronal responses to similar stimuli change dynamically over time, raising the question of
how internal representations can provide a stable substrate for neural coding. Recent work …

The phenomenon of policy churn

T Schaul, A Barreto, J Quan… - Advances in Neural …, 2022 - proceedings.neurips.cc
We identify and study the phenomenon of policy churn, that is, the rapid change of the
greedy policy in value-based reinforcement learning. Policy churn operates at a surprisingly …

[PDF][PDF] Two-photon synthetic aperture microscopy for minimally invasive fast 3D imaging of native subcellular behaviors in deep tissue

Z Zhao, Y Zhou, B Liu, J He, J Zhao, Y Cai, J Fan, X Li… - Cell, 2023 - cell.com
Holistic understanding of physio-pathological processes requires noninvasive 3D imaging in
deep tissue across multiple spatial and temporal scales to link diverse transient subcellular …

Self-healing codes: How stable neural populations can track continually reconfiguring neural representations

ME Rule, T O'Leary - … of the National Academy of Sciences, 2022 - National Acad Sciences
As an adaptive system, the brain must retain a faithful representation of the world while
continuously integrating new information. Recent experiments have measured population …

Long-term stability of single neuron activity in the motor system

KT Jensen, N Kadmon Harpaz, AK Dhawale… - Nature …, 2022 - nature.com
How an established behavior is retained and consistently produced by a nervous system in
constant flux remains a mystery. One possible solution to ensure long-term stability in motor …

Learning in a sensory cortical microstimulation task is associated with elevated representational stability

R Pancholi, L Ryan, S Peron - Nature communications, 2023 - nature.com
Sensory cortical representations can be highly dynamic, raising the question of how
representational stability impacts learning. We train mice to discriminate the number of …

[PDF][PDF] Exercise increases information content and affects long-term stability of hippocampal place codes

Y Rechavi, A Rubin, O Yizhar, Y Ziv - Cell Reports, 2022 - cell.com
Physical exercise is known to augment brain functioning, improving memory and cognition.
However, while some of the physiological effects of physical activity on the brain are known …

Learning leaves a memory trace in motor cortex

DM Losey, JA Hennig, ER Oby, MD Golub, PT Sadtler… - Current Biology, 2024 - cell.com
How are we able to learn new behaviors without disrupting previously learned ones? To
understand how the brain achieves this, we used a brain-computer interface (BCI) learning …

Drifting neuronal representations: Bug or feature?

P Masset, S Qin, JA Zavatone-Veth - Biological cybernetics, 2022 - Springer
The brain displays a remarkable ability to sustain stable memories, allowing animals to
execute precise behaviors or recall stimulus associations years after they were first learned …