Found throughout biology, polyvalent interactions are characterized by the simultaneous
binding of multiple ligands on one biological entity to multiple receptors on another (top part …

In recent years, substantial progress has been made in the understanding of the intracellular
lifestyle of Chlamydia trachomatis and how the bacteria establish themselves in the human …

A large library of phage-displayed human single-chain Fv antibodies (scFv), containing 6.7×
109 members, was generated by improving the steps of library construction. Fourteen …

The obligate intracellular bacterium Chlamydia trachomatis rapidly induces its own entry into
host cells. Initial attachment is mediated by electrostatic interactions to heparan sulfate …

A large array of glycoproteins, glycolipids, and proteoglycans decorate the surfaces of
animal cells. These glycoconjugates mediate many fundamental cellular processes …

Überall in der Biologie kommen polyvalente Wechselwirkungen vor. Sie zeichnen sich
durch die gleichzeitige Bindung mehrerer Liganden einer biologischen Einheit an mehrere …

During feeding by infected mosquitoes, malaria sporozoites are injected into the host's
bloodstream and enter hepatocytes within minutes. The remarkable target cell specificity of …

Glycosaminoglycans (GAGs) are complex polysaccharides, which play important roles in
cell growth, differentiation, morphogenesis, cell migration, and bacterial/viral infections …

Invasion of human mucosal cells by N. gonorrhoeae via the binding to heparansulfate
proteoglycan receptors is considered a crucial event of the infection. Using different human …

Chlamydia trachomatis undergoes its entire life cycle within an uncharacterized intracellular
vesicle that does not fuse with lysosomes. We used a fluorescent Golgi-specific probe,(N-[7 …