[HTML][HTML] In vitro biomimetic models for glioblastoma-a promising tool for drug response studies
T Stanković, T Ranđelović, M Dragoj, SS Burić… - Drug Resistance …, 2021 - Elsevier
The poor response of glioblastoma to current treatment protocols is a consequence of its
intrinsic drug resistance. Resistance to chemotherapy is primarily associated with …
intrinsic drug resistance. Resistance to chemotherapy is primarily associated with …
Hypoxia inducible factors in the tumor microenvironment as therapeutic targets of cancer stem cells
F Hajizadeh, I Okoye, M Esmaily, MG Chaleshtari… - Life sciences, 2019 - Elsevier
Cancer stem cells (CSC) constitute a small area of the tumor mass and are characterized by
self-renewal, differentiation and the ability to promote the development of secondary chemo …
self-renewal, differentiation and the ability to promote the development of secondary chemo …
The effect of hypoxia on photodynamic therapy with 5-aminolevulinic acid in malignant gliomas
T Ihata, N Nonoguchi, T Fujishiro, N Omura… - Photodiagnosis and …, 2022 - Elsevier
Background Glioblastoma (GBM) is a high-grade, poor prognosis tumor that is resistant to
standard treatment. The presence of a small number of glioma stem cells (GSCs) surviving …
standard treatment. The presence of a small number of glioma stem cells (GSCs) surviving …
Adaptive changes of glioblastoma cells following exposure to hypoxic (1% oxygen) tumour microenvironment
A Musah-Eroje, S Watson - International journal of molecular sciences, 2019 - mdpi.com
Glioblastoma multiforme is the most aggressive and malignant primary brain tumour, with a
median survival rate of between 15 to 17 months. Heterogeneous regions occur in …
median survival rate of between 15 to 17 months. Heterogeneous regions occur in …
Proteomics-based prognostic signature and nomogram construction of hypoxia microenvironment on deteriorating glioblastoma (GBM) pathogenesis
YD Wen, XS Zhu, DJ Li, Q Zhao, Q Cheng, Y Peng - Scientific Reports, 2021 - nature.com
The present study aimed to construct and evaluate a novel experiment-based hypoxia
signature to help evaluations of GBM patient status. First, the 426 proteins, which were …
signature to help evaluations of GBM patient status. First, the 426 proteins, which were …
Do patient-derived spheroid culture models have relevance in chondrosarcoma research?
R Ma, J Mandell, F Lu, T Heim… - Clinical Orthopaedics …, 2021 - journals.lww.com
Background In high-grade chondrosarcoma, 5-year survival is lower than 50%. Therefore, it
is important that preclinical models that mimic the disease with the greatest possible fidelity …
is important that preclinical models that mimic the disease with the greatest possible fidelity …
The role of Huntington protein in two models of stem cells: The Glioblastoma and the stem cells of the sub-ventricular zone
R Kassem - 2023 - theses.hal.science
Gliomas (GBM) are the most common and malignant form of brain tumors. Glioma cells are
largely resistant to available treatments including to the alkylating agent temozolomide …
largely resistant to available treatments including to the alkylating agent temozolomide …
[HTML][HTML] Carbonic anhydrase IX as a marker of hypoxia in gliomas: A narrative review
RE McLendon - Glioma, 2020 - journals.lww.com
Hypoxia is a powerful driver of the malignant phenotype in solid tumors including gliomas. A
major, though not sole, driver of this effect is the hypoxia-inducible factors (HIF) which …
major, though not sole, driver of this effect is the hypoxia-inducible factors (HIF) which …
[PDF][PDF] The effect of hypoxia on photodynamic therapy with 5-aminolevulinic acid in malignant gliomas
井畑知大, イハタトモヒロ - ompu.repo.nii.ac.jp
Background: Glioblastoma (GBM) is a high-grade, poor prognosis tumor that is resistant to
standard treatment. The presence of a small number of glioma stem cells (GSCs) surviving …
standard treatment. The presence of a small number of glioma stem cells (GSCs) surviving …
The Role of Microenviroment in Glioblastoma Progression and Resistance Development
T Randelovic, I Ochoa Garrido - zaguan.unizar.es
Glioma is the most common and aggressive type of malignant brain tumors. High-grade
gliomas, including WHO grade III (anaplastic astrocytoma and oligodendroglioma) and WHO …
gliomas, including WHO grade III (anaplastic astrocytoma and oligodendroglioma) and WHO …