Becker muscular dystrophy (BMD) is one of the most frequent among neuromuscular
diseases, affecting approximately 1 in 18,000 male births. It is linked to a genetic mutation …

Objective No treatments are approved for Becker muscular dystrophy (BMD). This study
investigated the efficacy and safety of givinostat, a histone deacetylase pan-inhibitor, in …

Background Becker muscular dystrophy (BMD) is a genetic neuromuscular disease of
growing importance caused by in‐frame, partial loss‐of‐function mutations in the dystrophin …

Mutations that prevent the production of proteins in the DMD gene cause Duchenne
muscular dystrophy. Most frequently, these are deletions leading to reading-frame shift. The …

Phospholamban is involved in the regulation of the activity and storage of calcium in cardiac
muscle. Several mutations have been identified in the PLN gene causing cardiac disease …

Background Becker muscular dystrophy (BMD) is an X‐linked disorder characterized by
slow, progressive muscle damage and muscle weakness. Hallmarks include fibre‐size …

Cell segmentation is a key step for a wide variety of biological investigations, especially in
the context of muscle science. Currently, automated methods still struggle to perform skeletal …

Limb girdle muscular dystrophies (LGMDs) are a group of genetically inherited
neuromuscular diseases with a very variable clinical presentation and overlapping traits …

Background Pathogenic missense variants in the dystrophin (DMD) gene are rarely reported
in dystrophinopathies. Most DMD missense variants are of uncertain significance and their …

Background: Becker muscular dystrophy is an X-linked, genetic disorder causing
progressive degeneration of skeletal and cardiac muscle, with a widely variable phenotype …