Understanding communication and information processing in nervous systems is a central
goal of neuroscience. Over the past two decades, advances in connectomics and network …

Many human brain disorders are associated with characteristic alterations in the structural
and functional connectivity of the brain. In this article, we explore how commonalities and …

Identifying effective treatments for Alzheimer's disease (AD) has proven challenging and has
instigated a shift in AD research focus toward the earliest disease-initiating cellular …

While shaped and constrained by axonal connections, fMRI-based functional connectivity
reorganizes in response to varying interareal input or pathological perturbations. However …

Over the past two decades, resting-state functional connectivity (RSFC) methods have
provided new insights into the network organization of the human brain. Studies of brain …

Neurodegenerative diseases are the most common cause of dementia. Although their
underlying molecular pathologies have been identified, there is substantial heterogeneity in …

Patterns of spontaneous brain activity, typically measured in humans at rest with fMRI, are
used routinely to assess the brain's functional organization. The mechanisms that generate …

Regular drug use can lead to addiction, but not everyone who takes drugs makes this
transition. How exactly drugs of abuse interact with individual vulnerability is not fully …

The default mode network (DMN) supports memory functioning and may be sensitive to
preclinical Alzheimer's pathology. Little is known, however, about the longitudinal trajectory …

Studies of brain network connectivity improved understanding on brain changes and
adaptation in response to different pathologies. Synaptic plasticity, the ability of neurons to …