Presentation, diagnosis and clinical course of the spectrum of progressive-fibrosing interstitial lung diseases

V Cottin, NA Hirani, DL Hotchkin… - European …, 2018 - Eur Respiratory Soc
Although these conditions are rare, a proportion of patients with interstitial lung diseases
(ILDs) may develop a progressive-fibrosing phenotype. Progressive fibrosis is associated …

[HTML][HTML] Biomarkers in the diagnosis and prognosis of sarcoidosis: current use and future prospects

R Kraaijvanger, M Janssen Bonás… - Frontiers in …, 2020 - frontiersin.org
Sarcoidosis is a heterogeneous disease in terms of presentation, duration, and severity. Due
to this heterogeneity, it is difficult to align treatment decisions. Biomarkers have proved to be …

[HTML][HTML] The role of diverse immune cells in sarcoidosis

H Zhang, U Costabel, H Dai - Frontiers in immunology, 2021 - frontiersin.org
Sarcoidosis is a systemic inflammatory disorder of unknown etiology characterized by tissue
infiltration with macrophages and lymphocytes and associated non-caseating granuloma …

Prognostic biomarkers of sarcoidosis: a comparative study of serum chitotriosidase, ACE, Lysozyme, and KL‐6

L Bergantini, F Bianchi, P Cameli, MA Mazzei… - Disease …, 2019 - Wiley Online Library
Purpose. Sarcoidosis is a systemic granulomatous disease with unknown etiology. Many
clinical presentations have been reported, and acute disease needs to be distinguished …

Sarcoidosis-associated pulmonary fibrosis: joining the dots

D Bandyopadhyay, MS Mirsaeidi - European Respiratory …, 2023 - Eur Respiratory Soc
Sarcoidosis is a multisystem granulomatous disorder of unknown aetiology. A minority of
patients with sarcoidosis develop sarcoidosis-associated pulmonary fibrosis (SAPF), which …

Moving target: shifting the focus to pulmonary sarcoidosis as an autoimmune spectrum disorder

Y Kaiser, A Eklund, J Grunewald - European Respiratory …, 2019 - Eur Respiratory Soc
Despite more than a century of research, the causative agent (s) in sarcoidosis, a
heterogeneous granulomatous disorder mainly affecting the lungs, remain (s) elusive …

[HTML][HTML] Expression of SAA1, SAA2 and SAA4 genes in human primary monocytes and monocyte-derived macrophages

C Jumeau, F Awad, E Assrawi, L Cobret… - PLoS …, 2019 - journals.plos.org
Circulating serum amyloid A (SAA) is increased in various inflammatory conditions. The
human SAA protein family comprises the acute phase SAA1/SAA2, known to activate a large …

New concepts in the pathogenesis of sarcoidosis

D Bennett, E Bargagli, RM Refini… - Expert Review of …, 2019 - Taylor & Francis
Introduction: The pathogenesis of sarcoidosis is not yet completely understood, although in
recent years our knowledge has made considerable progress. Areas covered: This review …

Management of cardiac sarcoidosis using mycophenolate mofetil as a steroid-sparing agent

JM Griffin, J Chasler, AL Wand, DR Okada… - Journal of cardiac …, 2021 - Elsevier
Background Cardiac sarcoidosis (CS) is a major cause of morbidity and mortality in patients
with systemic sarcoidosis. Steroid-sparing agents are increasingly used, despite a lack of …

[HTML][HTML] Next-generation sequencing based HLA typing: deciphering immunogenetic aspects of sarcoidosis

A Kishore, M Petrek - Frontiers in genetics, 2018 - frontiersin.org
Unraveling of the HLA-related immunogenetic basis of several immune disorders is complex
due to the extensive HLA polymorphism and strong linkage-disequilibrium between HLA …