[HTML][HTML] The phytochemical diversity of commercial Cannabis in the United States

CJ Smith, D Vergara, B Keegan, N Jikomes - PLoS one, 2022 - journals.plos.org
The legal status of Cannabis is changing, fueling an increasing diversity of Cannabis-
derived products. Because Cannabis contains dozens of chemical compounds with potential …

[HTML][HTML] Evolution, genetics and biochemistry of plant cannabinoid synthesis: a challenge for biotechnology in the years ahead

R Melzer, PF McCabe, S Schilling - Current Opinion in Biotechnology, 2022 - Elsevier
Cannabis sativa is most prominent for its psychoactive secondary compound
tetrahydrocannabinol, or THC. However, THC is only one of many phytocannabinoids found …

Comprehensive inventory of cannabinoids in Cannabis sativa L.: Can we connect genotype and chemotype?

BM Lange, JJ Zager - Phytochemistry Reviews, 2022 - Springer
Following decades of tight restrictions, recent legislative adjustments have decriminalized
the use of products derived from cannabis (Cannabis sativa L.) in many countries and …

[HTML][HTML] Profiling Cannabinoid Contents and Expression Levels of Corresponding Biosynthetic Genes in Commercial Cannabis (Cannabis sativa L.) Cultivars

AL Kim, YJ Yun, HW Choi, CH Hong, HJ Shim, JH Lee… - Plants, 2022 - mdpi.com
Cannabis (Cannabis sativa L.) is widely cultivated and studied for its psychoactive and
medicinal properties. As the major cannabinoids are present in acidic forms in Cannabis …

[HTML][HTML] Analysis of Sequence Variability and Transcriptional Profile of Cannabinoid synthase Genes in Cannabis sativa L. Chemotypes with a Focus on …

F Fulvio, R Paris, M Montanari, C Citti, V Cilento… - Plants, 2021 - mdpi.com
Cannabis sativa L. has been long cultivated for its narcotic potential due to the accumulation
of tetrahydrocannabinolic acid (THCA) in female inflorescences, but nowadays its …

Cannabinoids function in defense against chewing herbivores in Cannabis sativa L.

GM Stack, SI Snyder, JA Toth, MA Quade… - Horticulture …, 2023 - academic.oup.com
In the decades since the first cannabinoids were identified by scientists, research has
focused almost exclusively on the function and capacity of cannabinoids as medicines and …

[HTML][HTML] Genomic Evidence That Governmentally Produced Cannabis sativa Poorly Represents Genetic Variation Available in State Markets

D Vergara, EL Huscher, KG Keepers… - Frontiers in plant …, 2021 - frontiersin.org
The National Institute on Drug Abuse (NIDA) is the sole producer of Cannabis for research
purposes in the United States, including medical investigation. Previous research …

[HTML][HTML] The effect of cannabis plant extracts on head and neck squamous cell carcinoma and the quest for cannabis-based personalized therapy

K Blal, E Besser, S Procaccia, O Schwob, Y Lerenthal… - Cancers, 2023 - mdpi.com
Simple Summary The survival rate of head and neck cancer has only improved slightly over
the last quarter century, raising the need for novel therapies to better treat this disease. This …

[HTML][HTML] Multi-Omics Approaches to Study Molecular Mechanisms in Cannabis sativa

TM Sirangelo, RA Ludlow, ND Spadafora - Plants, 2022 - mdpi.com
Cannabis (Cannabis sativa L.), also known as hemp, is one of the oldest cultivated crops,
grown for both its use in textile and cordage production, and its unique chemical properties …

[HTML][HTML] The evolutionary origin of naturally occurring intermolecular Diels-Alderases from Morus alba

Q Ding, N Guo, L Gao, M McKee, D Wu, J Yang… - Nature …, 2024 - nature.com
Biosynthetic enzymes evolutionarily gain novel functions, thereby expanding the structural
diversity of natural products to the benefit of host organisms. Diels-Alderases (DAs) …