Root cultures, a boon for the production of valuable compounds: A comparative review

MJ Hussain, Y Abbas, N Nazli, S Fatima, S Drouet… - Plants, 2022 - mdpi.com
Medicinal plants are an inevitable source of pharmaceutical drugs and most of the world
population depends on these plants for health benefits. The increasing global demand for …

Phytoremediation and sequestration of soil metals using the CRISPR/Cas9 technology to modify plants: a review

N Bhattacharyya, U Anand, R Kumar, M Ghorai… - Environmental …, 2023 - Springer
Soil contamination by toxic metals is a major health issue that could be partly solved by
using genetically-modified plants. For that, the recently developed technique of clustered …

Plants as sources of natural and recombinant antimalaria agents

P Habibi, Y Shi, M Fatima Grossi-de-Sa, I Khan - Molecular biotechnology, 2022 - Springer
Malaria is one of the severe infectious diseases that has victimized about half a civilization
billion people each year worldwide. The application of long-lasting insecticides is the main …

Recent progress on vaccines produced in transgenic plants

G Gaobotse, S Venkataraman, KM Mmereke… - Vaccines, 2022 - mdpi.com
The development of vaccines from plants has been going on for over two decades now.
Vaccine production in plants requires time and a lot of effort. Despite global efforts in plant …

Hairy root cultures as a multitask platform for green biotechnology

A Gerszberg, A Wiktorek-Smagur - Plant Cell, Tissue and Organ Culture …, 2022 - Springer
Hairy root cultures serve as a useful tool in the experiments aiming to understand plant
biology (eg functional analysis of gene function) which affects their use in biotechnology …

Optimization of inside and outside factors to improve recombinant protein yield in plant

P Habibi, GS Prado, PB Pelegrini, KL Hefferon… - Plant Cell, Tissue and …, 2017 - Springer
The use of plant systems as factories for recombinant protein production became a
prominent alternative for pharmaceutical industries due to their high potential for protein …

Hairy root culture: a reliable bioreactor from transgenic plants

N Atabaki, NA Shaharuddin, SA Ahmad, R Nulit… - Peptide and protein drug …, 2024 - Elsevier
Plants can produce diverse arrays of specialized metabolites with different biological
activities, which are used as raw materials in cosmetics, flavors, fragrances, pigments, and …

Nanoparticle elicitation: A promising strategy to modulate the production of bioactive compounds in hairy roots

KM Mmereke, S Venkataraman, BN Moiketsi… - Food Research …, 2024 - Elsevier
Hairy root culture is one of the promising biotechnological tools to obtain the stable and
sustainable production of specialized metabolites from plants under controlled environment …

The potential of plant systems to break the HIV‐TB link

P Habibi, H Daniell, CR Soccol… - Plant Biotechnology …, 2019 - Wiley Online Library
Tuberculosis (TB) and human immunodeficiency virus (HIV) can place a major burden on
healthcare systems and constitute the main challenges of diagnostic and therapeutic …

Plant hairy roots: Induction, applications, limitations and prospects

Y Zhu, X Zhu, Y Wen, L Wang, Y Wang, C Liao… - Industrial Crops and …, 2024 - Elsevier
Hairy roots (HRs) are highly branched adventitious roots generated by the infection of plants
with Agrobacterium rhizogenes. Due to the fast growth rate, genetic stability, strong …