Glutamate receptor ion channels: structure, regulation, and function

SF Traynelis, LP Wollmuth, CJ McBain, FS Menniti… - Pharmacological …, 2010 - ASPET
The mammalian ionotropic glutamate receptor family encodes 18 gene products that
coassemble to form ligand-gated ion channels containing an agonist recognition site, a …

Optimizing pain management to facilitate enhanced recovery after surgery pathways

M Tan, LSL BSSc, TJ Gan - Canadian Journal of Anesthesia, 2015 - search.proquest.com
Conclusion There are continuing advancements in multimodal analgesic techniques;
however, postoperative pain in general continues to be undermanaged. Furthermore, a …

Persistent postsurgical pain: risk factors and prevention

H Kehlet, TS Jensen, CJ Woolf - The lancet, 2006 - thelancet.com
Acute postoperative pain is followed by persistent pain in 10–50% of individuals after
common operations, such as groin hernia repair, breast and thoracic surgery, leg …

[PDF][PDF] A systematic review of intravenous ketamine for postoperative analgesia

K Laskowski, A Stirling, WP Mckay… - Canadian Journal of …, 2011 - academia.edu
Résumé Objectif La ketamine intraveineuse perioperatoire peut constituer un ajout utile
al'arsenal therapeutique de prise en charge de la douleur. Les revues methodiques …

Transition from acute to chronic postsurgical pain: risk factors and protective factors

J Katz, Z Seltzer - Expert review of neurotherapeutics, 2009 - Taylor & Francis
Most patients who undergo surgery recover uneventfully and resume their normal daily
activities within weeks. Nevertheless, chronic postsurgical pain develops in an alarming …

The prevention of chronic postsurgical pain using gabapentin and pregabalin: a combined systematic review and meta-analysis

H Clarke, RP Bonin, BA Orser, M Englesakis… - Anesthesia & …, 2012 - journals.lww.com
BACKGROUND: Many clinical trials have demonstrated the effectiveness of gabapentin and
pregabalin administration in the perioperative period as an adjunct to reduce acute …

Intraoperative ketamine reduces perioperative opiate consumption in opiate-dependent patients with chronic back pain undergoing back surgery

RW Loftus, MP Yeager, JA Clark, JR Brown… - The Journal of the …, 2010 - pubs.asahq.org
Background Ketamine is an N-methyl-d-aspartate receptor antagonist that has been shown
to be useful in the reduction of acute postoperative pain and analgesic consumption in a …

[HTML][HTML] Efficacy of preemptive analgesia treatments for the management of postoperative pain: a network meta-analysis

C Xuan, W Yan, D Wang, C Li, H Ma, A Mueller… - British Journal of …, 2022 - Elsevier
Background Preemptive analgesia may improve postoperative pain management, but the
optimal regimen is unclear. This study aimed to compare the effects and adverse events of …

Remifentanil-induced postoperative hyperalgesia and its prevention with small-dose ketamine

V Joly, P Richebe, B Guignard, D Fletcher… - The Journal of the …, 2005 - pubs.asahq.org
Background Remifentanil-induced secondary hyperalgesia has been documented
experimentally in both animals and healthy human volunteers, but never clinically. This …

Peri‐operative intravenous administration of magnesium sulphate and postoperative pain: a meta‐analysis

E Albrecht, KR Kirkham, SS Liu, R Brull - Anaesthesia, 2013 - Wiley Online Library
Intravenous magnesium has been reported to improve postoperative pain; however, the
evidence is inconsistent. The objective of this quantitative systematic review is to evaluate …