Role of curcumin in the treatment of acute kidney injury: research challenges and opportunities

Y Cai, C Huang, M Zhou, S Xu, Y Xie, S Gao, Y Yang… - Phytomedicine, 2022 - Elsevier
Background Acute kidney injury (AKI) is a common complication in clinical inpatients, and it
continues a high morbidity and mortality rate despite many clinical treatment measures. AKI …

[HTML][HTML] Polyphenols and their metabolites in renal diseases: An overview

Í Guerreiro, C Ferreira-Pêgo, D Carregosa, CN Santos… - Foods, 2022 - mdpi.com
Kidney diseases constitute a worldwide public health problem, contributing to morbidity and
mortality. The present study aimed to provide an overview of the published data regarding …

Curcumin relieved cisplatin-induced kidney inflammation through inhibiting Mincle-maintained M1 macrophage phenotype

RZ Tan, J Liu, YY Zhang, HL Wang, JC Li, YH Liu… - Phytomedicine, 2019 - Elsevier
Background Acute kidney injury (AKI) is a common kidney disease with a high risk of death
and can develop into chronic kidney disease (CKD) and renal failure eventually. Curcumin …

Myalgic encephalomyelitis/chronic fatigue syndrome: From pathophysiological insights to novel therapeutic opportunities

G Morris, BK Puri, AJ Walker, M Maes… - Pharmacological …, 2019 - Elsevier
Myalgic encephalomyelitis (ME) or chronic fatigue syndrome (CFS) is a common and
disabling condition with a paucity of effective and evidence-based therapies, reflecting a …

[HTML][HTML] BRG1 regulates endothelial-derived IL-33 to promote ischemia-reperfusion induced renal injury and fibrosis in mice

L Liu, L Mao, X Wu, T Wu, W Liu, Y Yang… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Endothelial-derived factors regulate a wide range of pathophysiological events. It has been
reported previously that IL-33 promotes acute kidney injury (AKI) in mice although the …

The neuroprotective effects of curcumin are associated with the regulation of the reciprocal function between autophagy and HIF-1α in cerebral ischemia-reperfusion …

Y Hou, J Wang, J Feng - Drug Design, Development and Therapy, 2019 - Taylor & Francis
Purpose The beneficial, neuroprotective effects of curcumin against ischemia-reperfusion
injury have been demonstrated. In the present study, whether curcumin exerts …

Curcumin and LOXblock-1 ameliorate ischemia-reperfusion induced inflammation and acute kidney injury by suppressing the semaphorin-plexin pathway.

F Kar, C Hacioglu, H Senturk, DB Donmez, G Kanbak… - Life Sciences, 2020 - Elsevier
Abstract Aims Ischemia/reperfusion (I/R) is one of the most important causes of acute kidney
injury (AKI), a clinical syndrome with kidney dysfunction and high mortality rates. New …

[HTML][HTML] Retinal Protection and Distribution of Curcumin in Vitro and in Vivo

CBM Platania, A Fidilio, F Lazzara, C Piazza… - Frontiers in …, 2018 - frontiersin.org
Diabetic retinopathy (DR), a secondary complication of diabetes, is a leading cause of
irreversible blindness accounting for 5% of world blindness cases in working age. Oxidative …

Ameliorative role of curcumin on copper oxide nanoparticles‐mediated renal toxicity in rats: An investigation of molecular mechanisms

SA Elkhateeb, TR Ibrahim, AS El‐Shal… - … of Biochemical and …, 2020 - Wiley Online Library
The increasing role of copper oxide nanoparticles (CuO NPs) in many industries and their
broad range of applications increase its potential toxic effects. Curcumin possesses a wide …

[HTML][HTML] Effective nephroprotection against acute kidney injury with a star-shaped polyglutamate-curcuminoid conjugate

G Córdoba-David, A Duro-Castano… - Scientific Reports, 2020 - nature.com
The lack of effective pharmacological treatments for acute kidney injury (AKI) remains a
significant public health problem. Given the involvement of apoptosis and regulated necrosis …