Irreversible oxidative post-translational modifications in heart disease

T Tomin, M Schittmayer, S Honeder… - Expert review of …, 2019 - Taylor & Francis
Introduction: Development of specific biomarkers aiding early diagnosis of heart failure is an
ongoing challenge. Biomarkers commonly used in clinical routine usually act as readouts of …

Proteomics of the Heart

OA Karpov, A Stotland, K Raedschelders… - Physiological …, 2024 - journals.physiology.org
Mass spectrometry-based proteomics is a sophisticated identification tool specializing in
portraying protein dynamics at a molecular level. Proteomics provides biologists with a …

Biomarkers in heart failure: clinical insights

A Salzano, R D'Assante, MZ Israr… - Heart Failure …, 2021 - heartfailure.theclinics.com
Heart failure (HF) is a clinical syndrome caused by structural and/or functional cardiac
abnormalities and resulting from impaired cardiac output or an increase of intracardiac …

The current state of artificial intelligence in cardiac transplantation

R Goswami - Current opinion in organ transplantation, 2021 - journals.lww.com
Artificial intelligence applications with clinically relevant models in transplant medicine have
the potential to optimize organ utilization, prediction of complications, and potential …

[HTML][HTML] Proteomics in dogs: a systematic review

LG González-Arostegui, CP Rubio, JJ Cerón… - Research in Veterinary …, 2022 - Elsevier
Proteomic analysis is having a rapid development as a method for the detection of
biomarkers of diseases in dogs. Dogs in addition to their importance as companion animals …

Omics technologies in personalized combination therapy for cardiovascular diseases: challenges and opportunities

S Banerjee, N Prabhu Basrur, PS Rai - Personalized Medicine, 2021 - Future Medicine
The primary purpose of 'omics' technologies is to understand the intricacy of genomics,
proteomics, metabolomics and other molecular mechanisms to reveal the complex traits of …

Multi-omics approach: New potential key mechanisms implicated in cardiorenal syndromes

GM Virzì, A Clementi, GG Battaglia, C Ronco - Cardiorenal Medicine, 2019 - karger.com
Cardiorenal syndromes (CRS) include a scenario of clinical interactions characterized by
the heart and kidney dysfunction. The crosstalk between cardiac and renal systems is clearly …

Is the cardioprotective effect of the ACE2 activator diminazene aceturate more potent than the ACE inhibitor enalapril on acute myocardial infarction in rats?

NM Badae, AS El Naggar… - Canadian journal of …, 2019 - cdnsciencepub.com
Myocardial infarction is a major cause of cardiac dysfunction. All components of the cardiac
renin–angiotensin system (RAS) are upregulated in myocardial infarction. Angiotensin …

Mitoxantrone impairs proteasome activity and prompts early energetic and proteomic changes in HL-1 cardiomyocytes at clinically relevant concentrations

VM Costa, JP Capela, JR Sousa, RP Eleutério… - Archives of …, 2020 - Springer
Mitoxantrone (MTX) is used to treat several types of cancers and to improve neurological
disability in multiple sclerosis. Unfortunately, cardiotoxicity is a severe and common adverse …

High Throughput Plasma Proteomics and Risk of Heart Failure and Frailty in Late Life

D Ramonfaur, LF Buckley, V Arthur, Y Yang… - JAMA …, 2024 - jamanetwork.com
Importance Heart failure (HF) and frailty frequently coexist and may share a common
pathobiology, although the underlying mechanisms remain unclear. Understanding these …