Irreversible oxidative post-translational modifications in heart disease
Introduction: Development of specific biomarkers aiding early diagnosis of heart failure is an
ongoing challenge. Biomarkers commonly used in clinical routine usually act as readouts of …
ongoing challenge. Biomarkers commonly used in clinical routine usually act as readouts of …
Proteomics of the Heart
OA Karpov, A Stotland, K Raedschelders… - Physiological …, 2024 - journals.physiology.org
Mass spectrometry-based proteomics is a sophisticated identification tool specializing in
portraying protein dynamics at a molecular level. Proteomics provides biologists with a …
portraying protein dynamics at a molecular level. Proteomics provides biologists with a …
Biomarkers in heart failure: clinical insights
Heart failure (HF) is a clinical syndrome caused by structural and/or functional cardiac
abnormalities and resulting from impaired cardiac output or an increase of intracardiac …
abnormalities and resulting from impaired cardiac output or an increase of intracardiac …
The current state of artificial intelligence in cardiac transplantation
R Goswami - Current opinion in organ transplantation, 2021 - journals.lww.com
Artificial intelligence applications with clinically relevant models in transplant medicine have
the potential to optimize organ utilization, prediction of complications, and potential …
the potential to optimize organ utilization, prediction of complications, and potential …
[HTML][HTML] Proteomics in dogs: a systematic review
Proteomic analysis is having a rapid development as a method for the detection of
biomarkers of diseases in dogs. Dogs in addition to their importance as companion animals …
biomarkers of diseases in dogs. Dogs in addition to their importance as companion animals …
Omics technologies in personalized combination therapy for cardiovascular diseases: challenges and opportunities
S Banerjee, N Prabhu Basrur, PS Rai - Personalized Medicine, 2021 - Future Medicine
The primary purpose of 'omics' technologies is to understand the intricacy of genomics,
proteomics, metabolomics and other molecular mechanisms to reveal the complex traits of …
proteomics, metabolomics and other molecular mechanisms to reveal the complex traits of …
Multi-omics approach: New potential key mechanisms implicated in cardiorenal syndromes
Cardiorenal syndromes (CRS) include a scenario of clinical interactions characterized by
the heart and kidney dysfunction. The crosstalk between cardiac and renal systems is clearly …
the heart and kidney dysfunction. The crosstalk between cardiac and renal systems is clearly …
Is the cardioprotective effect of the ACE2 activator diminazene aceturate more potent than the ACE inhibitor enalapril on acute myocardial infarction in rats?
NM Badae, AS El Naggar… - Canadian journal of …, 2019 - cdnsciencepub.com
Myocardial infarction is a major cause of cardiac dysfunction. All components of the cardiac
renin–angiotensin system (RAS) are upregulated in myocardial infarction. Angiotensin …
renin–angiotensin system (RAS) are upregulated in myocardial infarction. Angiotensin …
Mitoxantrone impairs proteasome activity and prompts early energetic and proteomic changes in HL-1 cardiomyocytes at clinically relevant concentrations
Mitoxantrone (MTX) is used to treat several types of cancers and to improve neurological
disability in multiple sclerosis. Unfortunately, cardiotoxicity is a severe and common adverse …
disability in multiple sclerosis. Unfortunately, cardiotoxicity is a severe and common adverse …
High Throughput Plasma Proteomics and Risk of Heart Failure and Frailty in Late Life
D Ramonfaur, LF Buckley, V Arthur, Y Yang… - JAMA …, 2024 - jamanetwork.com
Importance Heart failure (HF) and frailty frequently coexist and may share a common
pathobiology, although the underlying mechanisms remain unclear. Understanding these …
pathobiology, although the underlying mechanisms remain unclear. Understanding these …