Abstract Histone Deacetylases (HDACs) deacetylate lysine residues in histone and non-
histone proteins. HDACs have been implicated in several diseases, including cancer …

Cardiac aging, particularly cardiac cell senescence, is a natural process that occurs as we
age. Heart function gradually declines in old age, leading to continuous heart failure, even in …

A novel photoelectrochemical (PEC) biosensor was constructed for histone deacetylase
Sirt1 detection based on the Z-Scheme heterojunction of CuS–BiVO 4 and reduced …

Inhibitors of histone deacetylases (HDACs) have received special attention as novel
anticancer agents. Among various types of synthetic inhibitors, benzamides constitute an …

Neuropathic pain affects millions of people in the worldwide, but the major therapeutics
perform limited effectiveness. Paeonol (PAE) is widely distributed in Paeonis albiflora, and …

A monolayer of endothelial cells (ECs) lines the lumen of blood vessels and, as such,
provides a semi-selective barrier between the blood and the interstitial space. Compromise …

Epigenetic changes play an important role in the pathophysiology of autoimmune diseases
such as allergic asthma, multiple sclerosis, lung diseases, diabetes, cystic fibrosis …

Background: Severe pneumonia is a kind of disease that develops from lung inflammation,
and new drugs are still required to treat the same. Erythropoietin (EPO) is widely used to …

Phenotypic switching between contractile (differentiated state) and proliferative
(dedifferentiated state) vascular smooth muscle cells (VSMCs) is a hallmark of vascular …

Objective: The aim of the present study is to investigate the effects of auraptene on
inflammation and apoptosis of pneumonia cell model and uncover the mechanism. Methods …