Identifying the steps required to effectively implement next-generation sequencing in oncology at a national level in Europe
Next-generation sequencing (NGS) may enable more focused and highly personalized
cancer treatment, with the National Comprehensive Cancer Network and European Society …
cancer treatment, with the National Comprehensive Cancer Network and European Society …
[HTML][HTML] Hallmarks of cancer: The CRISPR generation
C Moses, B Garcia-Bloj, AR Harvey… - European Journal of …, 2018 - Elsevier
The hallmarks of cancer were proposed as a logical framework to guide research efforts that
aim to understand the molecular mechanisms and derive treatments for this highly complex …
aim to understand the molecular mechanisms and derive treatments for this highly complex …
The emerging roles of NGS in clinical oncology and personalized medicine
Next-generation sequencing (NGS) has been increasingly popular in genomics studies over
the last decade, as new sequencing technology has been created and improved. Recently …
the last decade, as new sequencing technology has been created and improved. Recently …
Engineering in medicine to address the challenge of cancer drug resistance: from micro-and nanotechnologies to computational and mathematical modeling
Drug resistance has profoundly limited the success of cancer treatment, driving relapse,
metastasis, and mortality. Nearly all anticancer drugs and even novel immunotherapies …
metastasis, and mortality. Nearly all anticancer drugs and even novel immunotherapies …
A machine learning approach for somatic mutation discovery
Variability in the accuracy of somatic mutation detection may affect the discovery of
alterations and the therapeutic management of cancer patients. To address this issue, we …
alterations and the therapeutic management of cancer patients. To address this issue, we …
From genetics to genomics: facing the liability implications in clinical care
G Marchant, M Barnes, JP Evans, B LeRoy… - Journal of Law …, 2020 - cambridge.org
Health care is transitioning from genetics to genomics, in which single-gene testing for
diagnosis is being replaced by multi-gene panels, genome-wide sequencing, and other …
diagnosis is being replaced by multi-gene panels, genome-wide sequencing, and other …
Detection of COVID-19-related biomarkers by electrochemical biosensors and potential for diagnosis, prognosis, and prediction of the course of the disease in the …
V Vásquez, J Orozco - Analytical and bioanalytical chemistry, 2023 - Springer
As a more efficient and effective way to address disease diagnosis and intervention, cutting-
edge technologies, devices, therapeutic approaches, and practices have emerged within the …
edge technologies, devices, therapeutic approaches, and practices have emerged within the …
Recent developments in genetics and medically-assisted reproduction: from research to clinical applications
Two leading European professional societies, the European Society of Human Genetics and
the European Society for Human Reproduction and Embryology, have worked together …
the European Society for Human Reproduction and Embryology, have worked together …
A next-generation sequencing primer—how does it work and what can it do?
YO Alekseyev, R Fazeli, S Yang, R Basran… - Academic …, 2018 - journals.sagepub.com
Next-generation sequencing refers to a high-throughput technology that determines the
nucleic acid sequences and identifies variants in a sample. The technology has been …
nucleic acid sequences and identifies variants in a sample. The technology has been …
Effectiveness of PIVKA-II in the detection of hepatocellular carcinoma based on real-world clinical data
R Yu, Z Tan, X Xiang, Y Dan, G Deng - BMC cancer, 2017 - Springer
Abstract Background Protein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II) is an
efficient biomarker specific for hepatocellular carcinoma (HCC). Some researchers have …
efficient biomarker specific for hepatocellular carcinoma (HCC). Some researchers have …