Simple Summary Here we provide an overview of several genetically determined conditions
that predispose to the development of solid and hematologic malignancies in children …

Colon cancer is a common malignancy of the digestive tract with high morbidity and
mortality. There is an urgent need to identify effective biomarkers for the early diagnosis of …

A germline pathogenic variant may be present even if the results of tumor genomic
sequencing do not suggest one. There are key differences in the assay design and reporting …

Key message The study carry out comprehensive transcriptome analysis of C. deltoidea and
exploration of BIAs biosynthesis and accumulation based on UHPLC-MS/MS and combined …

Lack of relevant preclinical models that reliably recapitulate the complexity and
heterogeneity of human cancer has slowed down the development and approval of new anti …

Translating the power of high-throughput sequencing technologies from research area into
clinical medicine is one of the major goal for several researchers and health-care providers …

A growing number of studies investigating the association between Single Nucleotide
Polymorphisms (SNPs) and lung cancer risk have been published since over a decade ago …

Background Oral squamous cell carcinoma (OSCC) is a malignant cancer, the survival rate
of patients is disappointing. Therefore, it is necessary to identify the driven-genes and …

Introduction Increasing evidence leads to a ratiocination that genetic heterogeneity of the
lung adenocarcinoma with EGFR mutations may impact clinical responses and outcomes to …

Background Colon cancer is one of most malignant cancers around worldwide. Nearly 20%
patients were diagnosed at colon cancer with metastasis. However, the lack of …