Epidemiological evidence links an individual's susceptibility to chronic disease in adult life to
events during their intrauterine phase of development. Biologically this should not be …

Appropriate in utero growth is essential for offspring development and is a critical contributor
to long-term health. Fetal growth is largely dictated by the availability of nutrients in maternal …

Background: Pregnancy is a dynamic state involving multiple adaptations that are necessary
in order to ensure a continuous supply of essential metabolites to support the growth and the …

Abnormal fetal growth, both growth restriction and overgrowth, is associated with perinatal
complications and an increased risk of metabolic and cardiovascular disease later in life …

More glucose crosses the placenta than any other substrate, but correlations between its
concentration in maternal plasma and fetal growth are not found consistently. The …

Maternal lipids are strong determinants of fetal fat mass. Here we review the overall lipid
metabolism in normal and gestational diabetes mellitus (GDM) pregnancies. During early …

Background Evidence suggests that pre-pregnancy body mass index and gestational weight
gain have impact on pregnancy and birth weight, yet whether maternal gestational weight …

Essential fatty acids and their long chain polyunsaturated fatty acid derivatives (20° C) such
as docosahexaenoic and arachidonic acids are critical for proper fetal growth and …

We investigated the global placental gene expression profile in severe preeclampsia.
Twenty-one women were randomly selected from 50 participants with uncomplicated …

Intrauterine growth restriction (IUGR) correlates with a specific placental phenotype,
associated with defects in placental transport functions, that lead to fetal undernutrition. Both …