The glycoprotein follicle-stimulating hormone (FSH) acts on gonadal target cells, hence
regulating gametogenesis. The transduction of the hormone-induced signal is mediated by …

Follicular development is a highly coordinated process that in humans takes more than 6
months. Pituitary gonadotropins and a variety of locally produced growth factors and …

Estrogen is an important modulator of reproductive activity through nuclear receptors and G
protein–coupled estrogen receptor (GPER). Here, we observed that both estradiol and the …

Adenylate cyclase 1 (ADCY1 or AC1) is a member of ADCY superfamily and was primarily
found to be expressed in the brain. ADCY1 is responsible for catalyzing ATP to cyclic AMP …

Research question Does kaempferol alleviate postovulatory oocyte ageing, thereby
maintaining their early embryonic development capacity? Design The effects of kaempferol …

The cumulus cell-oocyte complex (COC) matrix is an extended coat that forms around the
oocyte a few hours before ovulation and plays vital roles in oocyte biology. Here, we …

Successful ovulation and oocyte fertilization are essential prerequisites for the beginning of
life in sexually reproducing animals. In mammalian fertilization, the relevance of the protein …

Peroxiredoxins (PRDXs) are expressed in the ovary and during ovulation. PRDX1 activity
related to the immuno-like response during ovulation is unknown. We investigated the roles …

The exploration of multiple birth-related genes has always been a significant focus in sheep
breeding. This study aimed to find more genes and proteins related to the litter size in sheep …

The surge in luteinizing hormone (LH) in preovulatory ovarian follicles triggers the
resumption of oocyte meiosis accompanied by expansion of surrounding cumulus cells and …