Effect of β2-adrenergic receptor polymorphism on response to longacting β2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled …
ME Wechsler, SJ Kunselman, VM Chinchilli, E Bleecker… - The Lancet, 2009 - thelancet.com
Background Some studies suggest that patients with asthma who are homozygous for
arginine at the 16th aminoacid position of the β 2-adrenergic receptor (B16 Arg/Arg) benefit …
arginine at the 16th aminoacid position of the β 2-adrenergic receptor (B16 Arg/Arg) benefit …
Pharmacogenetics of β2 adrenergic receptor gene polymorphisms, long‐acting β‐agonists and asthma
LP Chung, G Waterer… - Clinical & Experimental …, 2011 - Wiley Online Library
Cite this as: LP Chung, G. Waterer and PJ Thompson, Clinical & Experimental Allergy, 2011
(41) 312–326. Summary Adrenergic β2 receptor (ADRβ2) agonists are widely used in …
(41) 312–326. Summary Adrenergic β2 receptor (ADRβ2) agonists are widely used in …
Salmeterol/fluticasone propionate: a review of its use in asthma
K McKeage, SJ Keam - Drugs, 2009 - Springer
Summary Abstract Salmeterol/fluticasone propionate (Seretide/Advair Diskus®[dry powder
inhaler] or Seretide/Advair® inhalation aerosol [metered-dose inhaler]) is a fixed-dose …
inhaler] or Seretide/Advair® inhalation aerosol [metered-dose inhaler]) is a fixed-dose …
β2-Receptor Polymorphisms in Patients Receiving Salmeterol with or without Fluticasone Propionate
ER Bleecker, HS Nelson, M Kraft, J Corren… - American journal of …, 2010 - atsjournals.org
Rationale: Retrospective pharmacogenetic studies have questioned whether patients with
asthma who are arginine homozygous at the β2-adrenergic receptor (position 16) should …
asthma who are arginine homozygous at the β2-adrenergic receptor (position 16) should …
The role of pharmacogenomics in improving the management of asthma
S Kazani, ME Wechsler, E Israel - Journal of allergy and clinical …, 2010 - Elsevier
There is a large amount of interindividual variability in both therapeutic and adverse
responses to asthma therapies. Genetic variability can account for 50% to 60% of this …
responses to asthma therapies. Genetic variability can account for 50% to 60% of this …
抗哮喘药的药物基因组学研究进展
朱琳， 邓婕， 宋洪涛 - 中国医院药学杂志, 2011 - cqvip.com
目的: 综述三类常用抗哮喘药的药物基因组学研究进展. 方法: 通过对近年来的研究文献进行分析
, 整理和归纳. 较为全面地概况了β2 受体激动剂, 白三烯调节剂和糖皮质激素三类常用抗哮喘 …
, 整理和归纳. 较为全面地概况了β2 受体激动剂, 白三烯调节剂和糖皮质激素三类常用抗哮喘 …
[PDF][PDF] Association of beta2-adrenoceptor polymorphisms with asthma risk and therapeutic response: a meta-analysis and systematic review
L Zhang, J Zheng, H Wang, J Gong, L He, C Liu - Int J Clin Exp Med, 2018 - e-century.us
The contribution of beta2-adrenergic receptor (β2-AR) gene polymorphisms to the
development of asthma in the population is uncertain. We performed a meta-analysis to …
development of asthma in the population is uncertain. We performed a meta-analysis to …
[PDF][PDF] Study the Possible Role of β2 Adrenergic Receptor Gene in the Pathogenesis of Bronchial Hyperresponsiveness in Asthmatic Patients and its Relation to …
IM El Akkary, ZA El-Kholy, MM Mokhtar… - Journal of American …, 2012 - researchgate.net
Background and objectives: Several identified β2-adrenergic receptor (β2AR) gene
polymorphisms, including the amino acid substitution from arginine (Arg) to glycine (Gly) at …
polymorphisms, including the amino acid substitution from arginine (Arg) to glycine (Gly) at …
[PDF][PDF] β2-Receptor Polymorphisms in Patients Receiving Salmeterol with or without Fluticasone propionate
HG Ortega - 2009 - researchgate.net
Rationale: Retrospective pharmacogenetic studies have questioned whether asthma
patients who are Arginine homozygous at the β2-adrenergic receptor (position 16) should …
patients who are Arginine homozygous at the β2-adrenergic receptor (position 16) should …