Primary aldosteronism—a multidimensional syndrome

AF Turcu, J Yang, A Vaidya - Nature Reviews Endocrinology, 2022 - nature.com
Primary aldosteronism is a common cause of hypertension and is a risk factor for
cardiovascular and renal morbidity and mortality, via mechanisms mediated by both …

Approach to the patient with adrenal incidentaloma

I Bancos, A Prete - The Journal of Clinical Endocrinology & …, 2021 - academic.oup.com
Adrenal tumors are commonly discovered incidentally on cross-sectional abdominal
imaging performed for reasons other than adrenal mass. Incidence of adrenal tumors …

Neuroendocrine and adrenal tumors, version 2.2021, NCCN clinical practice guidelines in oncology

MH Shah, WS Goldner, AB Benson… - Journal of the National …, 2021 - jnccn.org
The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Neuroendocrine
and Adrenal Gland Tumors focus on the diagnosis, treatment, and management of patients …

Primary aldosteronism: state-of-the-art review

A Vaidya, GL Hundemer, K Nanba… - American Journal of …, 2022 - academic.oup.com
We are witnessing a revolution in our understanding of primary aldosteronism (PA). In the
past 2 decades, we have learned that PA is a highly prevalent syndrome that is largely …

Clinical, pathophysiologic, genetic, and therapeutic progress in primary bilateral macronodular adrenal hyperplasia

J Bertherat, I Bourdeau, L Bouys… - Endocrine …, 2023 - academic.oup.com
Patients with primary bilateral macronodular adrenal hyperplasia (PBMAH) usually present
bilateral benign adrenocortical macronodules at imaging and variable levels of cortisol …

Intraindividual variability of aldosterone concentrations in primary aldosteronism: implications for case detection

N Yozamp, GL Hundemer, M Moussa, J Underhill… - …, 2021 - Am Heart Assoc
Primary aldosteronism is an underdiagnosed cause of hypertension. Although inadequate
screening is one reason for underdiagnosis, another important contributor is that clinicians …

Screening rates for primary aldosteronism among individuals with hypertension plus hypokalemia: a population-based retrospective cohort study

GL Hundemer, H Imsirovic, A Vaidya, N Yozamp… - …, 2022 - Am Heart Assoc
Primary aldosteronism is a common, yet highly underdiagnosed, cause of hypertension that
leads to disproportionately high rates of cardiovascular disease. Hypertension plus …

Primary aldosteronism screening rates differ with sex, race, and comorbidities

AF Turcu, W Nhan, S Grigoryan, L Zhang… - Journal of the …, 2022 - Am Heart Assoc
Background Primary aldosteronism (PA) is a common but under‐recognized cause of
secondary hypertension. Data directly comparing screening rates across single and …

Aldosterone, renin, and aldosterone-to-renin ratio variability in screening for primary aldosteronism

E Ng, SM Gwini, R Libianto, KW Choy… - The Journal of …, 2023 - academic.oup.com
Context The plasma aldosterone concentration (PAC), renin, and aldosterone-to-renin ratio
(ARR) are used to screen for primary aldosteronism (PA). Substantial intra-individual …

Treating primary aldosteronism-induced hypertension: novel approaches and future outlooks

N Mullen, J Curneen, PT Donlon, P Prakash… - Endocrine …, 2024 - academic.oup.com
Primary aldosteronism (PA) is the most common cause of secondary hypertension and is
associated with increased morbidity and mortality when compared with blood pressure …